Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human (tested or 100% immunogen sequence identity)
IgM Monoclonal [SPM278]
Ammonium sulfate precipitation
IHC - Paraffin (1:25)
Specificity and Use
RPSA / Laminin Receptor antibody was raised against small cell lung carcinoma N592 live cells.
Human Laminin Receptor
Immunohistochemistry (formalin fixed paraffin embedded): 1:25 for 30 min at RT. Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10 min followed by cooling at RT for 20 min.
PBS, pH 7.4, 0.2% BSA, 0.05% sodium azide
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at 12 months.
RPSA Antibody, 37 kDa laminin receptor Antibody, 37LRP Antibody, 40S ribosomal protein SA Antibody, 67LR Antibody, 67 kDa laminin receptor Antibody, 37/67 kDa laminin receptor Antibody, 67kD, ribosomal protein SA Antibody, LAMR1 Antibody, LAMBR Antibody, Laminin receptor 1 Antibody, LamR Antibody, NEM/1CHD4 Antibody, SA Antibody, LRP/LR Antibody, Laminin binding protein Antibody, Laminin Receptor Antibody, LRP Antibody, p40 Antibody, Ribosomal protein SA Antibody
Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Many of the effects of laminin are mediated through interactions with cell surface receptors. These receptors include members of the integrin family, as well as non-integrin laminin-binding proteins.