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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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RPS6KB1 / P70S6K / S6K Antibody (aa384‑433) LS‑C117683
S6K antibody LS-C117683 is an unconjugated rabbit polyclonal antibody to S6K (RPS6KB1 / P70S6K) from human, mouse and rat. Validated for IHC, Peptide-ELISA and WB.
Catalog
Size
Price
LS-C117683-50
50 µl
Unavailable
LS-C117683-100
100 µl
Unavailable

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Product Description

S6K antibody LS-C117683 is an unconjugated rabbit polyclonal antibody to S6K (RPS6KB1 / P70S6K) from human, mouse and rat. Validated for IHC, Peptide-ELISA and WB.
About RPS6KB1 / P70S6K / S6K
Serine/threonine-protein kinase that acts downstream of mTOR signaling in response to growth factors and nutrients to promote cell proliferation, cell growth and cell cycle progression. Regulates protein synthesis through phosphorylation of EIF4B, RPS6 and EEF2K, and contributes to cell survival by repressing the pro-apoptotic function of BAD. Under conditions of nutrient depletion, the inactive form associates with the EIF3 translation initiation complex. P23443 NM_003161 NP_003152.1

RPS6KB1 Antibody, 70 kDa S6 kinase Antibody, p70 S6KA Antibody, p70-alpha Antibody, p70-S6K Antibody, p70 S6 kinase alpha Antibody, p70s6 kinase Antibody, S6K-beta-1 Antibody, STK14A Antibody, p70 ribosomal S6 kinase Antibody, p70 S6 kinase, alpha 1 Antibody, p70 S6 kinase, alpha 2 Antibody, p70 S6K-alpha Antibody, p70-S6K 1 Antibody, p70S6K Antibody, p70S6K1 Antibody, PS6K Antibody, Ribosomal protein S6 kinase I Antibody, S6K Antibody, S6K1 Antibody, p70 ribosomal S6 kinase alpha Antibody, p70(S6K)-alpha Antibody


Specifications

Target
Human RPS6KB1 / P70S6K / S6K
Host
Rabbit
Reactivity
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC (1:50 - 1:100)
  • Western blot (1:500 - 1:1000)
  • Peptide Enzyme-Linked Immunosorbent Assay (1:10000)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Failed Applications
  • IHC - Paraffin
Immunogen
Synthetic peptide from human p70 S6 Kinase (aa384-433).
Epitope
aa384-433
Specificity
p70 S6 Kinase (Ab-418) Antibody detects endogenous levels of total p70 S6 Kinase protein.
Presentation
PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol
Storage
Store at -20°C for up to 1 year.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Western blot

Western blot of extracts from COLO205/Jurkat/MCF-7/HeLa cells, using p70 S6 Kinase (Ab-418) Antibody. The lane on the right is treated with the synthesized peptide.
Western blot of extracts from COLO205/Jurkat/MCF-7/HeLa cells, using p70 S6 Kinase (Ab-418) Antibody. The lane on the right is treated with the synthesized peptide.

Western blot

Western blot of extracts from COLO205/Jurkat/MCF-7/HeLa cells, using p70 S6 Kinase (Ab-418) Antibody. The lane on the right is treated with the synthesized peptide.
Western blot of extracts from COLO205/Jurkat/MCF-7/HeLa cells, using p70 S6 Kinase (Ab-418) Antibody. The lane on the right is treated with the synthesized peptide.

Western blot

Western blot of extracts from COLO205/Jurkat/MCF-7/HeLa cells, using p70 S6 Kinase (Ab-418) Antibody. The lane on the right is treated with the synthesized peptide.
Western blot of extracts from COLO205/Jurkat/MCF-7/HeLa cells, using p70 S6 Kinase (Ab-418) Antibody. The lane on the right is treated with the synthesized peptide.

Western blot

Western blot of extracts from COLO205/Jurkat/MCF-7/HeLa cells, using p70 S6 Kinase (Ab-418) Antibody. The lane on the right is treated with the synthesized peptide.
Western blot of extracts from COLO205/Jurkat/MCF-7/HeLa cells, using p70 S6 Kinase (Ab-418) Antibody. The lane on the right is treated with the synthesized peptide.


Requested From: 
Date Requested: 6/19/2018

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