Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Serine/threonine-protein kinase that acts downstream of mTOR signaling in response to growth factors and nutrients to promote cell proliferation, cell growth and cell cycle progression. Regulates protein synthesis through phosphorylation of EIF4B, RPS6 and EEF2K, and contributes to cell survival by repressing the pro-apoptotic function of BAD. Under conditions of nutrient depletion, the inactive form associates with the EIF3 translation initiation complex.
Formalin-fixed and paraffin-embedded human breast carcinoma reacted with RPS6KB1 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Western blot of anti-RPS6KB1 Antibody antibody in Jurkat cell line lysates (35 ug/lane). RPS6KB1 Antibody )(arrow) was detected using the purified antibody.
Western blot of anti-RPS6KB1 Antibody antibody in 293 cell line lysates transiently transfected with the RPS6KB1 gene (2 ug/lane). RPS6KB1(arrow) was detected using the purified antibody.
Western blot of anti-RPS6KB1 Antibody antibody pre-incubated with and without blocking peptide (BP#NULL) in 293 cell line lysate. RPS6KB1 Antibody (arrow) was detected using the purified antibody.