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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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RPS6KA5 / MSK1 Antibody (phospho‑Ser376) LS‑C16609
MSK1 antibody LS-C16609 is an unconjugated rabbit polyclonal antibody to MSK1 (RPS6KA5) from human, mouse and rat. Validated for WB.
Antibody
Catalog
Size
Price
LS-C16609-100
100 µl
$575

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Product Description

MSK1 antibody LS-C16609 is an unconjugated rabbit polyclonal antibody to MSK1 (RPS6KA5) from human, mouse and rat. Validated for WB.
About RPS6KA5 / MSK1
Serine/threonine-protein kinase that is required for the mitogen or stress-induced phosphorylation of the transcription factors CREB1 and ATF1 and for the regulation of the transcription factors RELA, STAT3 and ETV1/ER81, and that contributes to gene activation by histone phosphorylation and functions in the regulation of inflammatory genes. Phosphorylates CREB1 and ATF1 in response to mitogenic or stress stimuli such as UV-C irradiation, epidermal growth factor (EGF) and anisomycin. O75582 NM_004755 NP_004746.2

RPS6KA5 Antibody, MSPK1 Antibody, RLPK Antibody, MSK1 Antibody, RSK-like protein kinase Antibody, RSKL Antibody, S6K-alpha-5 Antibody


Specifications

Target
Human RPS6KA5 / MSK1
Host
Rabbit
Reactivity
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Protein A purified
Modifications
Unmodified
Applications
  • Western blot (1:1000)
Immunogen
RPS6KA5 / MSK1 antibody was raised against synthetic phosphopeptide (KLH coupled) corresponding to residues surrounding Ser376 of human MSK1.
Epitope
pSer376
Specificity
Detects endogenous MSK1 only when phosphorylated at Ser376. Does not recognize MSK1 phosphorylated at other sites, nor does it recognize phosphorylated RSK1, RSK2 or RSK3. Species cross-reactivity: Human, mouse, and rat.
Usage
Suitable for use in Western Blot. Western Blot: 1:1000.
Presentation
10 mM HEPES, pH 7.5, 150 mM NaCl, 0.1 mg/ml BSA, 50% Glycerol, No preservatives added
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: United States
Date Requested: 8/16/2018

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