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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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RPS6KA5 / MSK1 Antibody (phospho‑Ser376) LS‑C117418
MSK1 antibody LS-C117418 is an unconjugated rabbit polyclonal antibody to MSK1 (RPS6KA5) from human and mouse. Validated for Peptide-ELISA and WB.
Catalog
Size
Price
LS-C117418-50
50 µl
Unavailable
LS-C117418-100
100 µl
Unavailable

Popular RPS6KA5 / MSK1 Products

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Western blot analysis of MSK1 (pT581) expression in HeLa UV-treated (A); 293 UV-treated (B); SP2/0 UV-treated (C); rat liver (D) whole cell lysates.
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Product Description

MSK1 antibody LS-C117418 is an unconjugated rabbit polyclonal antibody to MSK1 (RPS6KA5) from human and mouse. Validated for Peptide-ELISA and WB.
About RPS6KA5 / MSK1
Serine/threonine-protein kinase that is required for the mitogen or stress-induced phosphorylation of the transcription factors CREB1 and ATF1 and for the regulation of the transcription factors RELA, STAT3 and ETV1/ER81, and that contributes to gene activation by histone phosphorylation and functions in the regulation of inflammatory genes. Phosphorylates CREB1 and ATF1 in response to mitogenic or stress stimuli such as UV-C irradiation, epidermal growth factor (EGF) and anisomycin. O75582 NM_004755 NP_004746.2

RPS6KA5 Antibody, MSPK1 Antibody, RLPK Antibody, MSK1 Antibody, RSK-like protein kinase Antibody, RSKL Antibody, S6K-alpha-5 Antibody


Specifications

Target
Human RPS6KA5 / MSK1
Host
Rabbit
Reactivity
Human, Mouse (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot (1:500 - 1:1000)
  • Peptide Enzyme-Linked Immunosorbent Assay (1:20000)
Immunogen
RPS6KA5 / MSK1 antibody was raised against synthetic peptide from human MSK1 around the phosphorylation site of Ser376.
Epitope
pSer376
Specificity
MSK1 (Phospho-Ser376) Antibody detects endogenous levels of MSK1 only when phosphorylated at serine376.
Presentation
PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol
Storage
Store at -20°C for up to 1 year.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Western blot

Western blot of extracts from HUVEC cells treated with PMA 125 ng/ml 30', using MSK1 (Phospho-Ser376) Antibody. The lane on the right is treated with the synthesized peptide.
Western blot of extracts from HUVEC cells treated with PMA 125 ng/ml 30', using MSK1 (Phospho-Ser376) Antibody. The lane on the right is treated with the synthesized peptide.

Western blot

Western blot of extracts from HUVEC cells treated with PMA 125 ng/ml 30', using MSK1 (Phospho-Ser376) Antibody. The lane on the right is treated with the synthesized peptide.
Western blot of extracts from HUVEC cells treated with PMA 125 ng/ml 30', using MSK1 (Phospho-Ser376) Antibody. The lane on the right is treated with the synthesized peptide.

Western blot

Western blot of extracts from HUVEC cells treated with PMA 125 ng/ml 30', using MSK1 (Phospho-Ser376) Antibody. The lane on the right is treated with the synthesized peptide.
Western blot of extracts from HUVEC cells treated with PMA 125 ng/ml 30', using MSK1 (Phospho-Ser376) Antibody. The lane on the right is treated with the synthesized peptide.

Western blot

Western blot of extracts from HUVEC cells treated with PMA 125 ng/ml 30', using MSK1 (Phospho-Ser376) Antibody. The lane on the right is treated with the synthesized peptide.
Western blot of extracts from HUVEC cells treated with PMA 125 ng/ml 30', using MSK1 (Phospho-Ser376) Antibody. The lane on the right is treated with the synthesized peptide.


Requested From: 
Date Requested: 6/24/2018

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