Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone 1F6] (IgG2a,k) to Human RPS6KA2 / RSK3
IHC - Paraffin, Immunofluorescence, Western blot, ELISA
Human RPS6KA2 / RSK3
Human (tested or 100% immunogen sequence identity)
IgG2a,k Monoclonal [1F6]
Protein A purified
IHC - Paraffin (5 µg/ml)
Immunofluorescence (10 µg/ml)
Western blot (1:500 - 1:1000)
Specificity and Use
RPS6KA2 / RSK3 antibody was raised against rPS6KA2 (AAH02363, 631 a.a. ~ 733 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Immunohistochemistry: Formalin-fixed paraffin-embedded sections. RNAi Knockdown: Antibody validated. Western Blot using transfected cell lysates, cell line lysates and the recombinant protein used as the immunogen.
PBS, pH 7.2
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Serine/threonine-protein kinase that acts downstream of ERK (MAPK1/ERK2 and MAPK3/ERK1) signaling and mediates mitogenic and stress-induced activation of transcription factors, regulates translation, and mediates cellular proliferation, survival, and differentiation. May function as tumor suppressor in epithelial ovarian cancer cells.