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RPS3 / Ribosomal Protein S3

ribosomal protein S3

Involved in translation as a component of the 40S small ribosomal subunit (PubMed:8706699). Has endonuclease activity and plays a role in repair of damaged DNA (PubMed:7775413). Cleaves phosphodiester bonds of DNAs containing altered bases with broad specificity and cleaves supercoiled DNA more efficiently than relaxed DNA (PubMed:15707971). Displays high binding affinity for 7,8-dihydro-8-oxoguanine (8-oxoG), a common DNA lesion caused by reactive oxygen species (ROS) (PubMed:14706345). Has also been shown to bind with similar affinity to intact and damaged DNA (PubMed:18610840). Stimulates the N-glycosylase activity of the base excision protein OGG1 (PubMed:15518571). Enhances the uracil excision activity of UNG1 (PubMed:18973764). Also stimulates the cleavage of the phosphodiester backbone by APEX1 (PubMed:18973764). When located in the mitochondrion, reduces cellular ROS levels and mitochondrial DNA damage (PubMed:23911537). Has also been shown to negatively regulate DNA repair in cells exposed to hydrogen peroxide (PubMed:17049931). Plays a role in regulating transcription as part of the NF-kappa-B p65-p50 complex where it binds to the RELA/p65 subunit, enhances binding of the complex to DNA and promotes transcription of target genes (PubMed:18045535). Represses its own translation by binding to its cognate mRNA (PubMed:20217897). Binds to and protects TP53/p53 from MDM2-mediated ubiquitination (PubMed:19656744). Involved in spindle formation and chromosome movement during mitosis by regulating microtubule polymerization (PubMed:23131551). Involved in induction of apoptosis through its role in activation of CASP8 (PubMed:14988002). Induces neuronal apoptosis by interacting with the E2F1 transcription factor and acting synergistically with it to up-regulate pro-apoptotic proteins BCL2L11/BIM and HRK/Dp5 (PubMed:20605787). Interacts with TRADD following exposure to UV radiation and induces apoptosis by caspase-dependent JNK activation (PubMed:22510408).

Gene Name: ribosomal protein S3
Synonyms: RPS3, 40S ribosomal protein S3, IMR-90 ribosomal protein S3, S3, Ribosomal protein S3
Target Sequences: NM_001005 NP_000996.2 P23396

☰ Filters
Antibodies (34)
Proteins (7)
Over-Expression Lysate (2)
Primary (34)
Recombinant (5)
RPS3 / Ribosomal Protein S3 (41)
Human (34)
Mouse (22)
Rat (20)
Bovine (7)
Chicken (1)
Dog (7)
Guinea pig (6)
Horse (6)
Monkey (3)
Orangutan (3)
Pig (4)
Rabbit (6)
Xenopus (2)
Zebrafish (4)
IHC (14)
IHC-P (6)
WB (34)
ELISA (9)
ICC (3)
IF (7)
IP (5)
Peptide-ELISA (3)
rabbit (31)
mouse (3)
Product Group
IHCPlus (4)
IgG (17)
IgG1 (1)
IgG1,k (1)
IgG2a,k (1)
monoclonal mc (3)
polyclonal pc (31)
2A8 (1)
RP159-1 (1)
Biotin Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
Unconjugated (28)
C-Terminus (5)
aa116-165 (4)
140-220 aa, C-terminal (1)
aa1-50 (1)
aa160-209 (1)
aa171-220 (1)
aa193-243 (1)
No (41)
6His, N-terminus (1)
6His-SUMO, N-terminus (1)
GST (1)
GST, N-terminus (1)
His (1)
Myc-DDK (Flag) (2)
Fruit fly (1)
Human (5)
293T Cells (1)
E. coli (3)
HEK 293 Cells (1)
Wheat Germ Extract (2)
Purified (4)
RPS3 / Ribosomal Protein S3 Antibody - Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
RPS3 / Ribosomal Protein S3 Rabbit anti-Human Polyclonal (aa193-243) Antibody
Human
IHC, IHC-P, IP, WB
Unconjugated
50 µl/$460
RPS3 / Ribosomal Protein S3 Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
RPS3 / Ribosomal Protein S3 Mouse anti-Human Monoclonal (RP159-1) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
RPS3 / Ribosomal Protein S3 Antibody - RPS3 monoclonal antibody (M03), clone 2A8. Western Blot analysis of RPS3 expression in HeLa NE.
Select
RPS3 / Ribosomal Protein S3 Mouse anti-Human Monoclonal (2A8) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
RPS3 / Ribosomal Protein S3 Antibody - Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
RPS3 / Ribosomal Protein S3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, ICC, IHC, IHC-P, IP, WB
Unconjugated
50 µg/$460
RPS3 / Ribosomal Protein S3 Antibody - S3 / RPS3 antibody Western Blot of A549.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
RPS3 / Ribosomal Protein S3 Rabbit anti-Human Polyclonal (aa116-165) Antibody
Human
WB
Unconjugated
100 µl/$424
Select
RPS3 / Ribosomal Protein S3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ICC, IF, WB
Unconjugated
100 µl/$688
RPS3 / Ribosomal Protein S3 Antibody - Immunofluorescence analysis of HeLa cells.
Select
RPS3 / Ribosomal Protein S3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
RPS3 / Ribosomal Protein S3 Antibody - Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
RPS3 / Ribosomal Protein S3 Rabbit anti-Human Polyclonal (aa1-50) Antibody
Human
IHC, IHC-P, IP, WB
Unconjugated
50 µl/$460
RPS3 / Ribosomal Protein S3 Antibody - 1:100 staining human breast carcinoma tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
Select
RPS3 / Ribosomal Protein S3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Select
RPS3 / Ribosomal Protein S3 Rabbit anti-Human Polyclonal Antibody
Human
ICC, IF, IP, WB
Unconjugated
100 µl/$412
RPS3 / Ribosomal Protein S3 Antibody - Immunohistochemistry analysis of paraffin-embedded human tonsil tissue, using RPS3 Antibody. The picture on the right is blocked with the synthesized peptide.
Select
RPS3 / Ribosomal Protein S3 Rabbit anti-Human Polyclonal (aa171-220) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
Select
RPS3 / Ribosomal Protein S3 Mouse anti-Human Monoclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$371
Select
RPS3 / Ribosomal Protein S3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$341
Select
RPS3 / Ribosomal Protein S3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$341
Select
RPS3 / Ribosomal Protein S3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
RPS3 / Ribosomal Protein S3 Antibody - Western blot of Ribosomal Protein S3 antibody
Select
RPS3 / Ribosomal Protein S3 Rabbit anti-Human Polyclonal (140-220 aa, C-terminal) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
RPS3 / Ribosomal Protein S3 Antibody - Peptide - + Immunohistochemistry analysis of paraffin-embedded human tonsil tissue using RPS3 antibody.
Select
RPS3 / Ribosomal Protein S3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100 µg/$357
RPS3 / Ribosomal Protein S3 Antibody - Western blot analysis of the lysates from RAW264.7cells using RPS3 antibody.
Select
RPS3 / Ribosomal Protein S3 Rabbit anti-Human Polyclonal (aa160-209) Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
RPS3 / Ribosomal Protein S3 Antibody - IHC analysis of RPS3 using anti-RPS3 antibody. RPS3 was detected in paraffin-embedded section of human tonsil tissues. Heat mediated antigen retrieval was performed in citrate buffer (pH6, epitope retrieval solution) for 20 mins. The tissue section was blocked with 10% goat serum. The tissue section was then incubated with 1µg/ml rabbit anti-RPS3 Antibody overnight at 4°C. Biotinylated goat anti-rabbit IgG was used as secondary antibody and incubated for 30 minutes at 37°C. The tissue section was developed using Strepavidin-Biotin-Complex (SABC) with DAB as the chromogen.
Select
RPS3 / Ribosomal Protein S3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
Select
RPS3 / Ribosomal Protein S3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, WB
Unconjugated
50 µl/$356; 100 µl/$461
Select
RPS3 / Ribosomal Protein S3 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
RPS3 / Ribosomal Protein S3 Antibody - Immunofluorescence analysis of HeLa cells using RPS3 antibody. Blue: DAPI for nuclear staining.
Select
RPS3 / Ribosomal Protein S3 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
Select
RPS3 / Ribosomal Protein S3 Rabbit anti-Human Polyclonal Antibody
Human
IP, WB
Unconjugated
100 µl/$412
Select
RPS3 / Ribosomal Protein S3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
RPS3 / Ribosomal Protein S3 Antibody - RPS3 antibody Western blot of Fetal Kidney lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
RPS3 / Ribosomal Protein S3 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
Viewing 1-25 of 41 product results



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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).