Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Cnga1 is the alpha 1 subunit of cyclic nucleotide-gated (CNG) cation channels involved in visual and olfactory signal transduction. CNGalpha1-3 are able to form functional homooligomeric channels which control the flow of Na+ and Ca2+ into the outer segment of photoreceptor cells in response to light-induced changes in cGMP concentrations. The retinal rod cGMP-gated cation channel is a hetero-oligomer composed of the alpha subunit Cnga1 and a beta subunit.