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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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ROCK2 Antibody (N‑Terminus) LS‑C172063
Note: This antibody replaces LS-C312364
ROCK2 antibody LS-C172063 is an unconjugated rabbit polyclonal antibody to ROCK2 from human, mouse and rat. Validated for IHC and WB.
Catalog
Size
Price
LS-C172063-100
100 µg
Unavailable

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Product Description

ROCK2 antibody LS-C172063 is an unconjugated rabbit polyclonal antibody to ROCK2 from human, mouse and rat. Validated for IHC and WB.
About ROCK2
Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. Involved in regulation of smooth muscle contraction, actin cytoskeleton organization, stress fiber and focal adhesion formation, neurite retraction, cell adhesion and motility via phosphorylation of ADD1, BRCA2, CNN1, EZR, DPYSL2, EP300, MSN, MYL9/MLC2, NPM1, RDX, PPP1R12A and VIM. Phosphorylates SORL1 and IRF4. Acts as a negative regulator of VEGF-induced angiogenic endothelial cell activation. O75116 NM_004850 NP_004841.2

ROCK2 Antibody, KIAA0619 Antibody, p164 ROCK-2 Antibody, Rho kinase 2 Antibody, RhoA-associated kinase-2 Antibody, ROCK-II Antibody, Rho kinase II Antibody, Rok beta Antibody, Rok2 Antibody, RockII Antibody


Specifications

Target
Human ROCK2
Host
Rabbit
Reactivity
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin
  • Western blot
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
ROCK2 antibody was raised against synthetic peptide corresponding to a sequence at the N-terminal of human ROCK2, identical to the related rat and mouse sequence.
Epitope
N-Terminus
Specificity
Human, mouse, rat. No cross reactivity with other proteins.
Presentation
5 mg BSA, 0.9 mg sodium chloride, 0.2 mg sodium phosphate, 0.05 mg Thimerosal, 0.05 mg sodium azide
Storage
Short term: 4°C; Long term: -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


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Western blot

Immunohistochemistry

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Immunohistochemistry

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Immunohistochemistry

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Requested From: 
Date Requested: 6/18/2018

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