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Anti-ROCK2 Antibody (clone 1E12) IHC-plus™ LS-B4486

Note: This antibody replaces LS-C105082

Ordering

Wt. Vol. Conc. Price
50 µg - 0.27 mg/ml $450
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular ROCK2 Antibodies

Anti-ROCK2 Antibody (phospho-Tyr256) LS-C60110
Rabbit Polyclonal to Human ROCK2
Human
Western blot, ELISA
Unconjugated
Western blot Image
Anti-ROCK2 Antibody (clone 1E12) IHC-plus™ LS-B4486
Mouse Monoclonal [clone 1E12] (IgG1,k) to Human ROCK2
Human
IHC - Paraffin, Immunofluorescence, Western blot, ELISA
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Mouse Monoclonal [clone 1E12] (IgG1,k) to Human ROCK2
Human
IHC - Paraffin, Immunofluorescence, Western blot, ELISA
Unconjugated

Details

Human ROCK2
Mouse
Human (tested or 100% immunogen sequence identity)
IgG1,k Monoclonal [1E12]
Unconjugated
Protein A purified
Unmodified

Applications

  • IHC - Paraffin (5 µg/ml)
  • Immunofluorescence (30 µg/ml)
  • Western blot
  • ELISA

Specificity and Use

ROCK2 antibody was raised against rOCK2 (NP_004841, 1279 a.a. ~ 1389 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Western Blot (Cell lysate) - positive control Hela NE. Immunofluorescence (30 ug/ml) - positive control HeLa cells.

Packaging

PBS, pH 7.4.
Store at -20°C. Aliquot to avoid freeze/thaw cycles.
For research use only.

About ROCK2

O75116 NM_004850 NP_004841.2

ROCK2 Antibody, KIAA0619 Antibody, p164 ROCK-2 Antibody, Rho kinase 2 Antibody, RhoA-associated kinase-2 Antibody, ROCK-II Antibody, Rho kinase II Antibody, Rok beta Antibody, Rok2 Antibody, RockII Antibody

Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. Involved in regulation of smooth muscle contraction, actin cytoskeleton organization, stress fiber and focal adhesion formation, neurite retraction, cell adhesion and motility via phosphorylation of ADD1, BRCA2, CNN1, EZR, DPYSL2, EP300, MSN, MYL9/MLC2, NPM1, RDX, PPP1R12A and VIM. Phosphorylates SORL1 and IRF4. Acts as a negative regulator of VEGF-induced angiogenic endothelial cell activation.

Immunohistochemistry

Immunohistochemistry
Anti-ROCK2 antibody IHC of human vessel. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4486 concentration 5 ug/ml.

Immunofluorescence

Immunofluorescence
Immunofluorescence of monoclonal antibody to ROCK2 on HeLa cell (antibody concentration 30 ug/ml).

Western blot

Western blot
ROCK2 monoclonal antibody, clone 1E12 Western blot of ROCK2 expression in HeLa NE.
 

Requested From: United States
Date Requested: 12/6/2016

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