ROCK2

Rho-associated, coiled-coil containing protein kinase 2

Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. Involved in regulation of smooth muscle contraction, actin cytoskeleton organization, stress fiber and focal adhesion formation, neurite retraction, cell adhesion and motility via phosphorylation of ADD1, BRCA2, CNN1, EZR, DPYSL2, EP300, MSN, MYL9/MLC2, NPM1, RDX, PPP1R12A and VIM. Phosphorylates SORL1 and IRF4. Acts as a negative regulator of VEGF-induced angiogenic endothelial cell activation. Positively regulates the activation of p42/MAPK1-p44/MAPK3 and of p90RSK/RPS6KA1 during myogenic differentiation. Plays an important role in the timely initiation of centrosome duplication. Inhibits keratinocyte terminal differentiation. May regulate closure of the eyelids and ventral body wall through organization of actomyosin bundles. Plays a critical role in the regulation of spine and synaptic properties in the hippocampus. Plays an important role in generating the circadian rhythm of the aortic myofilament Ca2+ sensitivity and vascular contractility by modulating the myosin light chain phosphorylation.

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ROCK2 (69)

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Human (57)

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rabbit (49)

mouse (1)

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IHC-plus™ ROCK2 Antibody (clone 1E12) LS-B4486

(4.0) Rating

Antibody:

ROCK2 Mouse anti-Human Monoclonal (1E12) Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$460

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Human ROCK2 (Sandwich ELISA) ELISA Kit - LS-F22011

(4.0) Rating

(1) Publication(s)

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

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ROCK2 Antibody (phospho-Tyr256) LS-C60110

Antibody:

ROCK2 Rabbit anti-Human Polyclonal (pTyr256) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$567

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ROCK2 Antibody LS-C334228

Antibody:

ROCK2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, IP, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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ROCK2 Antibody (aa1109-1388) LS-C376532

Antibody:

ROCK2 Rabbit anti-Human Polyclonal (aa1109-1388) Antibody

Reactivity:

Rat, Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$294; 100 µl/$360

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Human ROCK2 Protein (Recombinant His-T7) (aa904-1140) - LS-G14364

Source:

E. coli

Tag:

His-T7

Molecular Weight:

31.1 kDa

Price:

50 µg/$440; 10 µg/$281; 200 µg/$877; 100 µg/$702; 1 mg/$1,983; 500 µg/$1,523; 5 mg/$3,067; 2 mg/$2,170

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Mouse/Human/Rat ROCK2 (Sandwich ELISA) ELISA Kit - LS-F9189

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse, Human, Rat

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$856

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ROCK2 Antibody (p722) LS-C825683

Antibody:

ROCK2 Rabbit anti-Human Polyclonal (p722) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$357

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IHC-plus™ ROCK2 Antibody LS-B7101

(4.0) Rating

Antibody:

ROCK2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

0.05 mg/$460

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ROCK2 Antibody LS-C660579

Antibody:

ROCK2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, IP, WB

Format:

Unconjugated

Price:

100 µg/$341

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ROCK2 Antibody LS-C660580

Antibody:

ROCK2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

100 µg/$341

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ROCK2 Antibody (aa511-560) LS-B6964

Antibody:

ROCK2 Rabbit anti-Human Polyclonal (aa511-560) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P

Format:

Unconjugated

Price:

100 µl/$485

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ROCK2 Antibody (N-Terminus, Sepharose) LS-C172065

Antibody:

ROCK2 Rabbit anti-Human Polyclonal (N-Terminus) (Sepharose) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IP

Format:

Sepharose Conjugated

Price:

100 µg/$399

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Human ROCK2 (Sandwich ELISA) ELISA Kit - LS-F51074

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

31.2 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$1,041

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Mouse ROCK2 (Sandwich ELISA) ELISA Kit - LS-F18662

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

1.56 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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ROCK2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G116315

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

160.7 kDa

Price:

100 µg/$710

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ROCK2 Antibody LS-C490068

Antibody:

ROCK2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µg/$575

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ROCK2 Antibody (aa652-923) LS-C357576

Antibody:

ROCK2 Rabbit anti-Human Polyclonal (aa652-923) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

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ROCK2 Antibody (N-Terminus) LS-C122396

Antibody:

ROCK2 Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µg/$564

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ROCK2 Antibody (N-Terminus) LS-C172063

Antibody:

ROCK2 Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µg/$380

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ROCK2 Antibody LS-C341296

Antibody:

ROCK2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

50 µl/$356; 100 µl/$461

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ROCK2 Antibody LS-C742588

Antibody:

ROCK2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

Select

ROCK2 Antibody (660-740 aa) LS-C385938

Antibody:

ROCK2 Rabbit anti-Human Polyclonal (660-740 aa) Antibody

Reactivity:

Mouse, Rat, Human, Monkey

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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ROCK2 Antibody LS-C679343

Antibody:

ROCK2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

Select

ROCK2 Antibody LS-C742942

Antibody:

ROCK2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

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