Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Roundabout (Robo) is a class of neural guidance receptors that bind slit ligands and mediated axonal repulsion and inhibition of leukocyte migrations. In addition to neural expression, Robo4 shows expression in endothelial cells of the vasculature, placenta, and tumors. It has been shown to play a role in embryonic angiogenesis. Studies in mice showed expression restricted to endothelial cells.
Roundabout 4 Antibody IHC of formalin-fixed and paraffin-embedded prostate carcinoma followed by peroxidase-conjugated secondary antibody and DAB staining. This data demonstrates the use of the Roundabout 4 Antibody for immunohistochemistry.
Roundabout 4 Antibody western blot of 293,K562,HL-60 cell line lysates (35 ug/lane). The Roundabout4 antibody detected the Roundabout4 protein (arrow).
Roundabout 4 Antibody flow cytometry of 293 cells (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Requested From: United States
Date Requested: 10/27/2016