Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Roundabout (Robo) is a class of neural guidance receptors that bind slit ligands and mediated axonal repulsion and inhibition of leukocyte migrations. In addition to neural expression, Robo4 shows expression in endothelial cells of the vasculature, placenta, and tumors. It has been shown to play a role in embryonic angiogenesis. Studies in mice showed expression restricted to endothelial cells.
Anti-ROBO4 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6693 concentration 5 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Detection of ROBO4 in HUVEC cell lysates with LS-B6693. This image was taken for the unconjugated form of this product. Other forms have not been tested.