Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse-Balb/c Monoclonal [clone 58-15] (IgM) to Mouse RNP
IHC - Paraffin, IHC - Frozen, Flow Cytometry
IgM Monoclonal [58-15]
IHC - Paraffin
IHC - Frozen
Specificity and Use
RNP antibody was raised against isolated nuclei. Splenocytes were fused with mouse myeloma NS-1 cells.
Identifies cells active in the cell cycle and hence can be used to measure themitotic activity of cell populations. Since the antibody can be used in paraffin embedded tissue sections, it can identify actively cycling cells within routinely fixed tissue specimens.
For flowcytometry the cells have to be madepermeable and incubation with 58-15 antibody should be carried out at 37° C.