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RNF31

ring finger protein 31

E3 ubiquitin-protein ligase component of the LUBAC complex which conjugates linear ('Met-1'-linked) polyubiquitin chains to substrates and plays a key role in NF-kappa-B activation and regulation of inflammation. LUBAC conjugates linear polyubiquitin to IKBKG and RIPK1 and is involved in activation of the canonical NF-kappa-B and the JNK signaling pathways. Linear ubiquitination mediated by the LUBAC complex interferes with TNF-induced cell death and thereby prevents inflammation. LUBAC is proposed to be recruited to the TNF-R1 signaling complex (TNF-RSC) following polyubiquitination of TNF-RSC components by BIRC2 and/or BIRC3 and to conjugate linear polyubiquitin to IKBKG and possibly other components contributing to the stability of the complex. Together with FAM105B/otulin, the LUBAC complex regulates the canonical Wnt signaling during angiogenesis. Binds polyubiquitin of different linkage types.

Gene Name: ring finger protein 31
Synonyms: RNF31, HOIP, HOIL-1-interacting protein, Ring finger protein 31, ZIBRA
Target Sequences: NM_017999 NP_060469.4 Q96EP0

☰ Filters
Antibodies (25)
Proteins (2)
ELISA Kits (1)
Custom (1)
Over-Expression Lysate (2)
Primary (25)
RNF31 (28)
Human (26)
Mouse (4)
Rat (1)
Bat (1)
Bovine (1)
Chimpanzee (3)
Dog (1)
Gibbon (3)
Guinea pig (3)
Horse (3)
Monkey (4)
Pig (1)
Rabbit (4)
IHC (5)
IHC-P (2)
WB (20)
ELISA (11)
IF (2)
IP (1)
Peptide-ELISA (2)
rabbit (24)
goat (1)
IgG (21)
polyclonal pc (25)
96-Well Microplate (1)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (1)
Unconjugated (14)
aa955-983 (7)
C-Terminus (4)
aa1022-1072 (1)
aa908-921 (1)
aa950-1000 (1)
No (28)
Myc-DDK (Flag) (2)
Human (1)
293T Cells (1)
HEK 293 Cells (1)
RNF31 Antibody - Immunohistochemistry of paraffin-embedded human kidney tissue using antibody at dilution of 1:100.
Select
RNF31 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
Select
RNF31 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA, IHC
HRP Conjugated
50 µg/$294; 100 µg/$360
Select
RNF31 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, IHC
Biotin Conjugated
50 µg/$294; 100 µg/$360
Select
RNF31 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA, IHC
FITC Conjugated
50 µg/$294; 100 µg/$360
Select
RNF31 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
RNF31 Antibody - Western Blot: RNF31 Antibody - Analysis of RNF31 (HOIP) using RNF31 antibody. Human rectum probed with RNF31 antibody at 5 ug/ml.
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RNF31 Rabbit anti-Human Polyclonal (aa950-1000) Antibody
Human
IHC, IHC-P, WB
Unconjugated
0.1 mg/$386
Select
RNF31 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$341
Select
RNF31 Rabbit anti-Human Polyclonal (aa955-983) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
Select
RNF31 Rabbit anti-Human Polyclonal (aa955-983) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
RNF31 Rabbit anti-Human Polyclonal (aa955-983) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
Select
RNF31 Rabbit anti-Human Polyclonal (aa955-983) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
Select
RNF31 Rabbit anti-Human Polyclonal (aa955-983) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
Select
RNF31 Rabbit anti-Human Polyclonal (aa955-983) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
RNF31 Antibody - Detection of Human RNF31 by Western Blot. Samples: Samples: Whole cell lysate from HeLa (15 and 50 ug), 293T (T; 50 ug) and Jurkat (J; 50 ug) cells. Antibodies: Affinity purified rabbit anti-RNF31 antibody used for WB at 0.4 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.
Select
RNF31 Rabbit anti-Human Polyclonal (aa1022-1072) Antibody
Mouse, Human
IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
RNF31 Antibody - Immunofluorescence analysis of Human breast using RNF31 Polyclonal Antibody at dilution of 1:100 (40x lens).Blue: DAPI for nuclear staining.
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RNF31 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
RNF31 Antibody - Antibody staining (2 ug/ml) of HepG2 lysate (RIPA buffer, 30 ug total protein per lane). Primary incubated for 1 hour. Detected by Western blot of chemiluminescence.
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RNF31 Goat anti-Human Polyclonal (aa908-921) Antibody
Rabbit, Dog, Bovine, Pig, Bat, Human, Monkey
Peptide-ELISA, WB
Unconjugated
100 µg/$503
RNF31 Antibody - Sample (30 ug of whole cell lysate) A: IMR32 7.5% SDS PAGE RNF31 antibody diluted at 1:500
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RNF31 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µl/$408
RNF31 Antibody - RNF31 antibody Western blot of Jurkat lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
RNF31 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
RNF31 Antibody - RNF31 antibody Western blot of Jurkat lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
RNF31 Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody
Rabbit, Guinea pig, Horse, Gibbon, Human, Monkey, Chimpanzee
WB
HRP Conjugated
100 µl/$469
RNF31 Antibody - RNF31 antibody Western blot of Jurkat lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
RNF31 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody
Rabbit, Guinea pig, Horse, Gibbon, Human, Monkey, Chimpanzee
WB
Biotin Conjugated
100 µl/$469
RNF31 Antibody - RNF31 antibody Western blot of Jurkat lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
RNF31 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody
Rabbit, Guinea pig, Horse, Gibbon, Human, Monkey, Chimpanzee
WB
FITC Conjugated
100 µl/$469
RNF31 Antibody - RNF31 Antibody western blot of CEM cell line lysates (35 ug/lane). The RNF31 antibody detected the RNF31 protein (arrow).
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RNF31 Rabbit anti-Human Polyclonal (aa955-983) Antibody
Human
WB
Unconjugated
400 µl/$393
RNF31 Antibody - Western blot analysis of extracts of various cell lines, using RNF31 antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 90s.
Select
RNF31 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
RNF31 Antibody - Western blot analysis of extracts of various cell lines.
Select
RNF31 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
RNF31 Antibody - Western blot analysis of RNF31 expression in MCF7 (A); HeLa (B); PC3 (C) whole cell lysates.
Select
RNF31 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
50 µl/$286; 100 µl/$321; 200 µl/$386
Viewing 1-25 of 28 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).