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Anti-RNF213 Antibody (aa5191-5204) IHC-plus™ LS-B1757

Note: This antibody replaces LS-C47583
Catalog Size Price
LS-B1757-50 50 µg (0.5 mg/ml) Unavailable

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100% Guaranteed
Goat Polyclonal to Human RNF213
Human
IHC - Paraffin, ELISA
Unconjugated

Details

Human RNF213
Goat
Human (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • IHC - Paraffin (1.25 µg/ml)
  • ELISA (1:128000)

Specificity and Use

RNF213 antibody was raised against synthetic peptide C-KNPQTQTEERFRPQ from an internal region of human RNF213 (NP_065965.3). Percent identity with other species by BLAST analysis: Human (100%), Gorilla (93%).
LS-E26260 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-B1757. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
aa5191-5204
Human RNF213.
Immunohistochemistry: LS-B1757 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B1757 was determined to be 1.25 ug/ml.

Packaging

Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Store at -20°C. Avoid freeze-thaw cycles.
For research use only.

About RNF213

Q63HN8 NM_020954 NP_066005.2

RNF213 Antibody, C17orf27 Antibody, KIAA1618 Antibody, KIAA1554 Antibody, Mysterin Antibody, MYSTR Antibody, ALO17 Antibody, Moyamoya disease 2 Antibody, MYMY2 Antibody, NET57 Antibody, Ring finger protein 213 Antibody

RNF213 is a protein containing a C3HC4-type RING finger domain, which is a specialized type of Zn-finger that binds two atoms of zinc and is thought to be involved in mediating protein-protein interactions. The protein also contains an AAA domain, which is associated with ATPase activity. This gene is a susceptibility gene for Moyamoya disease, a vascular disorder of intracranial arteries.

Immunohistochemistry

Immunohistochemistry
Anti-RNF213 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1757 concentration 25 ug/ml.

Requested From: 
Date Requested: 8/21/2017

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