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Anti-RNF139 / TRC8 Antibody (Internal) LS-C153494

Catalog Size Price
LS-C153494-100 100 µg (1 mg/ml) Unavailable

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100% Guaranteed
Rabbit Polyclonal to S. pombe RNF139 / TRC8
S. pombe
IHC, Western blot, ELISA


S. pombe RNF139 / TRC8
S. pombe (tested or 100% immunogen sequence identity)
Protein A purified


  • IHC
  • Western blot

Specificity and Use

RNF139 / TRC8 antibody was raised against synthetic peptide derived from internal domain of RCA1 protein of Schizosaccharomyces pombe.
Reacts with 85kD RCA1 protein from Schizosaccharomyces pombe.


100 mM Tris-glycine, 2% sucrose
100 µl Distilled water
Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at 4°C. For extended periods store in aliquots at -20°C.
For research use only.

About RNF139 / TRC8

Q8WU17 NM_007218 NP_009149.2

RNF139 Antibody, HRCA1 Antibody, RCA1 Antibody, TRC8 Antibody, Ring finger protein 139 Antibody

E3-ubiquitin ligase; acts as a negative regulator of the cell proliferation through mechanisms involving G2/M arrest and cell death. Required for MHC class I ubiquitination in cells expressing the cytomegalovirus protein US2 before dislocation from the endoplasmic reticulum (ER). Affects SREBP processing by hindering the SREBP/SCAP complex translocation from the ER to the Golgi, thereby reducing SREBF2 target gene expression. Required for INSIG1 ubiquitination.

Requested From: 
Date Requested: 1/20/2018

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