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RNF139 / TRC8

ring finger protein 139

E3-ubiquitin ligase; acts as a negative regulator of the cell proliferation through mechanisms involving G2/M arrest and cell death. Required for MHC class I ubiquitination in cells expressing the cytomegalovirus protein US2 before dislocation from the endoplasmic reticulum (ER). Affects SREBP processing by hindering the SREBP/SCAP complex translocation from the ER to the Golgi, thereby reducing SREBF2 target gene expression. Required for INSIG1 ubiquitination. May be required for EIF3 complex ubiquitination. May function as a signaling receptor.

Gene Name: ring finger protein 139
Synonyms: RNF139, HRCA1, RCA1, TRC8, Ring finger protein 139
Target Sequences: NM_007218 NP_009149.2 Q8WU17

☰ Filters
Antibodies (11)
Proteins (4)
Over-Expression Lysate (2)
Primary (11)
Recombinant (2)
RNF139 / TRC8 (15)
Human (10)
Mouse (3)
Rat (3)
Bat (3)
Bovine (3)
Dog (3)
Gibbon (3)
Guinea pig (3)
Monkey (1)
Orangutan (3)
Pig (3)
Rabbit (3)
S. pombe (1)
IHC (9)
IHC-P (7)
WB (9)
ELISA (4)
Peptide-ELISA (2)
rabbit (8)
mouse (1)
goat (1)
rabbit-new zealand white (1)
Product Group
IHCPlus (2)
IgG (6)
IgG1,k (1)
monoclonal mc (1)
polyclonal pc (10)
3D10 (1)
Biotin Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
Unconjugated (8)
aa72-121 (4)
Internal (1)
aa500-550 (1)
aa604-636 (1)
aa651-663 (1)
No (15)
GST (1)
GST, N-terminus (1)
Myc-DDK (Flag) (2)
Human (3)
293T Cells (1)
HEK 293 Cells (1)
Wheat Germ Extract (2)
Purified (1)
RNF139 / TRC8 Antibody - Anti-RNF139 / TRC8 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 3.75 ug/ml.
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RNF139 / TRC8 Goat anti-Human Polyclonal (aa651-663) Antibody
Human, Monkey
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
RNF139 / TRC8 Antibody - All lanes: Anti-RNF139 Antibody (C-Term) at 1:2000 dilution. Lane 1: Caki-1 whole cell lysate. Lane 2: human brain lysate. Lane 3: human heart lysate. Lane 4: human kidney lysate Lysates/proteins at 20 ug per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1:10000 dilution. Predicted band size: 76 kDa. Blocking/Dilution buffer: 5% NFDM/TBST.
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RNF139 / TRC8 Rabbit anti-Human Polyclonal (aa604-636) Antibody
Human
Peptide-ELISA, WB
Unconjugated
200 µl/$393
RNF139 / TRC8 Antibody - Anti-RNF139 / TRC8 antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5-10 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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RNF139 / TRC8 Rabbit anti-Human Polyclonal (aa72-121) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
RNF139 / TRC8 Antibody - Anti-RNF139 / TRC8 antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5-10 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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RNF139 / TRC8 Rabbit anti-Human Polyclonal (aa72-121) (HRP) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Pig, Bat, Gibbon, Orangutan, Human
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
RNF139 / TRC8 Antibody - Anti-RNF139 / TRC8 antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5-10 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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RNF139 / TRC8 Rabbit anti-Human Polyclonal (aa72-121) (Biotin) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Pig, Bat, Gibbon, Orangutan, Human
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
RNF139 / TRC8 Antibody - Anti-RNF139 / TRC8 antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5-10 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
RNF139 / TRC8 Rabbit anti-Human Polyclonal (aa72-121) (FITC) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Pig, Bat, Gibbon, Orangutan, Human
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
Select
RNF139 / TRC8 Rabbit anti-S. pombe Polyclonal (Internal) Antibody
S. pombe
ELISA, IHC, WB
Unconjugated
50 µg/$440; 100 µg/$480
RNF139 / TRC8 Antibody - Immunohistochemistry of paraffin-embedded human kidney tissue at dilution of 1:100
Select
RNF139 / TRC8 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
RNF139 / TRC8 Antibody - Immunohistochemistry of paraffin-embedded human kidney tissue at dilution of 1:100
Select
RNF139 / TRC8 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
RNF139 / TRC8 Antibody - RNF139 monoclonal antibody (M01), clone 3D10 Western blot of RNF139 expression in HepG2.
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RNF139 / TRC8 Mouse anti-Human Monoclonal (3D10) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
Select
RNF139 / TRC8 Rabbit-New Zealand White anti-Human Polyclonal (aa500-550) Antibody
Human
IHC, WB
Unconjugated
100 µl/$393
RNF139 / TRC8 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
RNF139 / TRC8 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
75.8 kDa
20 µg/$150
RNF139 / TRC8 Protein - 12.5% SDS-PAGE of human RNF139 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
102.4 kDa
10 µg/$479; 25 µg/$670
RNF139 / TRC8 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
75.8 kDa
100 µg/$494
Viewing 1-15 of 15 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).