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RNASE2 / EDN

ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)

This is a non-secretory ribonuclease. It is a pyrimidine specific nuclease with a slight preference for U. Cytotoxin and helminthotoxin. Selectively chemotactic for dendritic cells. Possesses a wide variety of biological activities.

Gene Name: ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
Synonyms: RNASE2, EDN, Eosinophil-derived neurotoxin, Ribonuclease US, RNase 2, RNase UpI-2, RNS2, Non-secretory ribonuclease, Ribonuclease 2
Target Sequences: NM_002934 NP_002925.1 P10153

Publications (1)

1
Mast Cell and Eosinophil Activation Are Associated With COVID-19 and TLR-Mediated Viral Inflammation: Implications for an Anti-Siglec-8 Antibody. Simon Gebremeskel, Julia Schanin, Krysta M Coyle, Melina Butuci, Thuy Luu, Emily C Brock, Alan Xu, Alan Wong, John Leung, Wouter Korver, Ryan D Morin, Robert P Schleimer, Bruce S Bochner, Bradford A Youngblood. Frontiers in immunology. 2021 March;12:650331. [Full Text Article] [PubMed:33777047] [PMC:PMC7988091]

☰ Filters
Antibodies (27)
ELISA Kits (5)
Proteins (4)
Primary (27)
Recombinant (4)
Sandwich (5)
RNASE2 / EDN (36)
Human (31)
Mouse (1)
Pig (1)
IHC (5)
IHC-P (5)
WB (26)
ELISA (11)
ICC (8)
IP (7)
rabbit (27)
Product Group
IHCPlus (1)
IgG (16)
polyclonal pc (27)
96-Well Microplate (1)
96-Well Strip Plate (4)
APC (1)
APC Conjugated (3)
Azide-free (1)
Biotin Conjugated (4)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (4)
HRP Conjugated (4)
PE Conjugated (3)
Unconjugated (7)
aa124-152 (7)
aa1-161 (1)
No (35)
Yes (1)
Plasma (5)
Serum (5)
Tissue Homogenates (2)
6His, N-terminus (1)
GST (1)
GST, N-terminus (1)
His-SUMO, N-terminus (1)
Human (4)
E. coli (2)
Wheat Germ Extract (2)
Purified (1)
RNASE2 / EDN Antibody - Western blot of lysate from human spleen tissue lysate, using RNASE2 Antibody. Antibody was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L (HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug per lane.
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RNASE2 / EDN Rabbit anti-Human Polyclonal (aa124-152) Antibody
Human
WB
Unconjugated
400 µl/$393
RNASE2 / EDN ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
6.25 - 400 U/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
RNASE2 / EDN Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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RNASE2 / EDN Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
RNASE2 / EDN Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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RNASE2 / EDN Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA, IHC, IHC-P, WB
HRP Conjugated
50 µg/$294; 100 µg/$360
RNASE2 / EDN Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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RNASE2 / EDN Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, IHC, IHC-P, WB
Biotin Conjugated
50 µg/$294; 100 µg/$360
RNASE2 / EDN Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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RNASE2 / EDN Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA, IHC, IHC-P, WB
FITC Conjugated
50 µg/$294; 100 µg/$360
RNASE2 / EDN ELISA Kit
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Sandwich
96-Well Strip Plate
Pig
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
RNASE2 / EDN Protein - Recombinant Ribonuclease A2 (RNASE2) by SDS-PAGE
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E. coli
His-SUMO, N-terminus
32kDa
10 µg/$275; 50 µg/$407; 200 µg/$812; 100 µg/$652; 1 mg/$1,893; 500 µg/$1,444; 5 mg/$2,843; 2 mg/$2,077
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E. coli
6His, N-terminus
19.6 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
RNASE2 / EDN ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$834
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RNASE2 / EDN Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
20 µl/$478; 100 µl/$919
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RNASE2 / EDN Rabbit anti-Human Polyclonal Antibody
Human
ICC, WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
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RNASE2 / EDN Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ICC, IP, WB
HRP Conjugated
100 µl/$338; 200 µl/$393; 500 µl/$575; 1 ml/$702; 2 ml/$939; 5 ml/$1,593
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RNASE2 / EDN Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ICC, IP, WB
Biotin Conjugated
100 µl/$319; 200 µl/$365; 500 µl/$519; 1 ml/$596; 2 ml/$824; 5 ml/$1,348
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RNASE2 / EDN Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ICC, IP, WB
FITC Conjugated
100 µl/$348; 200 µl/$407; 500 µl/$605; 1 ml/$755; 2 ml/$993; 5 ml/$1,716
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RNASE2 / EDN Rabbit anti-Human Polyclonal (APC) Antibody
Human
ICC, IP, WB
APC Conjugated
100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451
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RNASE2 / EDN Rabbit anti-Human Polyclonal (APC, Cy7) Antibody
Human
ICC, IP, WB
APC, Cy7 Conjugated
100 µl/$505; 200 µl/$648; 500 µl/$1,152; 1 ml/$1,401; 2 ml/$1,961; 5 ml/$3,676
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RNASE2 / EDN Rabbit anti-Human Polyclonal (Cy3) Antibody
Human
ICC, IP, WB
Cy3 Conjugated
100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451
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RNASE2 / EDN Rabbit anti-Human Polyclonal (PE) Antibody
Human
ICC, IP, WB
PE Conjugated
100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451
RNASE2 / EDN ELISA Kit
Select
Sandwich
96-Well Microplate
Human
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
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RNASE2 / EDN Rabbit anti-Human Polyclonal (aa124-152) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
Select
RNASE2 / EDN Rabbit anti-Human Polyclonal (aa124-152) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
RNASE2 / EDN Rabbit anti-Human Polyclonal (aa124-152) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
Select
RNASE2 / EDN Rabbit anti-Human Polyclonal (aa124-152) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
Select
RNASE2 / EDN Rabbit anti-Human Polyclonal (aa124-152) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
Viewing 1-25 of 36 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).