Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Forgot password?
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Quick Order
Products
Antibodies
ELISA and Assay Kits
Research Areas
Infectious Disease
Resources
Purchasing
Reference Material
Contact Us
Locations
Orders Processing,
Shipping & Receiving,
Warehouse
2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
Production Lab
Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
Telephone Numbers
Tel: +1 (206) 374-1102
Fax: +1 (206) 577-4565
Contact Us
Additional Contact Details
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Forgot password?
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Quick Order
RIPK3 / RIP3
receptor-interacting serine-threonine kinase 3
Essential for necroptosis, a programmed cell death process in response to death-inducing TNF-alpha family members. Upon induction of necrosis, RIPK3 interacts with, and phosphorylates RIPK1 and MLKL to form a necrosis-inducing complex. RIPK3 binds to and enhances the activity of three metabolic enzymes: GLUL, GLUD1, and PYGL. These metabolic enzymes may eventually stimulate the tricarboxylic acid cycle and oxidative phosphorylation, which could result in enhanced ROS production.
| Gene Name: | receptor-interacting serine-threonine kinase 3 |
| Family/Subfamily: | Protein Kinase , RIP |
| Synonyms: | RIPK3, Receptor interacting protein 3, RIP-like protein kinase 3, RIP3, RIP-3, Receptor-interacting protein 3 |
| Target Sequences: | NM_006871 NP_006862.2 Q9Y572 |
Publications (2)
1
The effects and regulatory mechanism of RIP3 on RGC-5 necroptosis following elevated hydrostatic pressure. Shang L, Ding W, Li N, Liao L, Chen D, Huang J, Xiong K. Acta biochimica et biophysica Sinica. 2017 February;49:128-137. [Full Text Article]
[PubMed:28039150]
Related Antibodies: LS-C97217.
2
A phosphorylation of RIPK3 kinase initiates an intracellular apoptotic pathway that promotes prostaglandin2a-induced corpus luteum regression. Dianrong Li, Jie Chen, Jia Guo, Lin Li, Gaihong Cai, She Chen, Jia Huang, Hui Yang, Yinhua Zhuang, Fengchao Wang, Xiaodong Wang. eLife. 2021 May;10: [Full Text Article]
[PubMed:34029184]
[PMC:PMC8143796]
Related Antibodies: LS-C336804.
☰ Filters
Products
Antibodies
(109)
Proteins
(11)
ELISA Kits
(7)
Type
Primary
(109)
Recombinant
(11)
Sandwich
(7)
Target
RIPK3 / RIP3
(127)
Reactivity
Human
(92)
Mouse
(41)
Rat
(16)
Chimpanzee
(3)
Gibbon
(3)
Horse
(3)
Monkey
(7)
Application
IHC
(62)
IHC-P
(24)
WB
(102)
ELISA
(28)
IF
(11)
IP
(2)
Peptide-ELISA
(1)
Host
rabbit
(85)
mouse
(24)
Product Group
IHCPlus
(3)
Isotype
IgG
(46)
IgG1
(13)
IgG1,k
(1)
IgG2a
(6)
IgG2b
(4)
Clonality
monoclonal mc
(24)
polyclonal pc
(85)
Clone
2013CT892.86.49
(1)
OTI1B3
(2)
OTI1D8
(2)
OTI1D9
(2)
OTI1H1
(2)
OTI2B10
(2)
OTI2C11
(2)
OTI2F11
(2)
OTI2F12
(2)
OTI2H8
(2)
OTI3A12
(2)
OTI3A3
(2)
Format
96-Well Strip Plate
(7)
AP Conjugated
(1)
APC
(2)
APC Conjugated
(6)
Atto 390 Conjugated
(1)
Atto 488 Conjugated
(1)
Atto 594 Conjugated
(1)
Azide-free
(3)
Biotin Conjugated
(10)
Carrier-free
(11)
Cy3 Conjugated
(2)
Cy7 Conjugated
(2)
FITC Conjugated
(10)
HRP Conjugated
(9)
MaxLight 550 Conjugated
(1)
PE Conjugated
(5)
PerCP Conjugated
(1)
Preservative Free
(1)
RPE Conjugated
(1)
Unconjugated
(58)
Epitope
aa233-518
(22)
aa16-239
(8)
aa50-272
(8)
aa61-91
(8)
aa1-30
(7)
aa480-509
(7)
aa168-217
(4)
aa251-300
(4)
aa38-87
(4)
aa489-518
(2)
Internal
(1)
Ser316
(1)
aa1-120
(1)
aa400-450
(1)
aa473-486
(1)
aa480-518
(1)
aa480-530
(1)
aa60-76
(1)
Publications
No
(125)
Yes
(2)
Sample Type
Cell Lysates
(3)
Plasma
(4)
Serum
(4)
Tissue Homogenates
(4)
Tag
10His, N-terminus + Myc, C-terminus
(1)
6His, N-terminus
(2)
6His-SUMO, N-terminus
(1)
GST
(1)
GST, N-terminus
(3)
GST, N-terminus + His, C-terminus
(1)
His-T7
(2)
Species
Human
(8)
Mouse
(2)
Rat
(1)
Source
Baculovirus
(1)
E. coli
(4)
Sf9 Cells
(2)
Wheat Germ Extract
(2)
Yeast
(2)
Purification
Purified
(4)
RIPK3 / RIP3 Rabbit anti-Human Polyclonal (aa489-518) Antibody
Mouse, Human
IHC, WB
Unconjugated
400 µl/$393
RIPK3 / RIP3 Rabbit anti-Human Polyclonal (aa480-530) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µg/$440
RIPK3 / RIP3 Mouse anti-Human Monoclonal (aa233-518) (OTI1B3) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
RIPK3 / RIP3 Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Human
WB
Unconjugated
100 µl/$299
RIPK3 / RIP3 Mouse anti-Human Monoclonal (aa233-518) (OTI2F12) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
E. coli
6His-SUMO, N-terminus
1 mg/$1,355; 100 µg/$420; 20 µg/$323
Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
Yeast
6His, N-terminus
55.32 kD
100 µg/$499; 20 µg/$364; 1 mg/$1,683
Sandwich
96-Well Strip Plate
Rat
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$768
RIPK3 / RIP3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
0.1 mg/$460
RIPK3 / RIP3 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, IHC
Biotin Conjugated
50 µg/$294; 100 µg/$360
RIPK3 / RIP3 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA, IHC
FITC Conjugated
50 µg/$294; 100 µg/$360
RIPK3 / RIP3 Mouse anti-Human Monoclonal (aa233-518) (OTI1D9) Antibody
Human
WB
Unconjugated
100 µl/$434
E. coli
His-T7
28.5 kDa
10 µg/$280; 50 µg/$437; 100 µg/$700; 200 µg/$872; 1 mg/$1,978; 500 µg/$1,519; 5 mg/$3,053; 2 mg/$2,164
RIPK3 / RIP3 Rabbit anti-Human Polyclonal (aa61-91) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
RIPK3 / RIP3 Rabbit anti-Human Polyclonal (Biotin) Antibody
Mouse, Human
IF, IHC, WB
Biotin Conjugated
100 µg/$477
RIPK3 / RIP3 Rabbit anti-Human Polyclonal (FITC) Antibody
Mouse, Human
IF, IHC, WB
FITC Conjugated
100 µg/$473
RIPK3 / RIP3 Rabbit anti-Human Polyclonal (aa168-217) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$397
RIPK3 / RIP3 Rabbit anti-Human Polyclonal (aa489-518) Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
RIPK3 / RIP3 Rabbit anti-Human Polyclonal (aa61-91) (Azide-free) (HRP) Antibody
Mouse, Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
RIPK3 / RIP3 Rabbit anti-Human Polyclonal (aa61-91) (MaxLight 550) Antibody
Mouse, Human
IHC, WB
MaxLight 550 Conjugated
100 µl/$952
RIPK3 / RIP3 Rabbit anti-Human Polyclonal (aa480-509) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
RIPK3 / RIP3 Rabbit anti-Human Polyclonal (aa400-450) Antibody
Human
IHC, IHC-P, IP, WB
Unconjugated
50 µl/$460
RIPK3 / RIP3 Rabbit anti-Human Polyclonal (aa251-300) Antibody
Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
Viewing 1-25
of 127
product results
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.
