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Anti-RIPK3 / RIP3 Antibody (aa473-486) LS-C187829

Ordering

Wt. Vol. Conc. Price
100 µg - 1 mg/ml $330
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular RIPK3 / RIP3 Antibodies

Anti-RIPK3 / RIP3 Antibody (aa480-530) IHC-plus™ LS-B1769
Rabbit Polyclonal (IgG) to Human RIPK3 / RIP3
Human
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-RIPK3 / RIP3 Antibody (aa489-518) LS-C97217
Rabbit Polyclonal to Human RIPK3 / RIP3
Human, Mouse
IHC, Western blot
Unconjugated
Immunohistochemistry Image
Anti-RIPK3 / RIP3 Antibody (Internal, Azide-free, HRP) LS-C282304
Rabbit Polyclonal (IgG) to Human RIPK3 / RIP3
Human, Mouse
IHC, Western blot, ELISA
HRP Conjugated, Azide-free

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal (IgG) to Mouse RIPK3 / RIP3
Mouse, Rat
IHC - Paraffin, Western blot
Unconjugated

Details

Mouse RIPK3 / RIP3
Rabbit
Mouse, Rat (tested or 100% immunogen sequence identity)
IgG Polyclonal
Unconjugated
Affinity purified
Unmodified

Applications

  • IHC - Paraffin (5 µg/ml)
  • Western blot (0.5 - 1 µg/ml)

Specificity and Use

RIPK3 / RIP3 antibody was raised against synthetic peptide sequence corresponding to amino acids 473-486 of mouse RIP3.
aa473-486
Recognizes mouse serine-threonine kinase receptor-interacting protein 3 (RIP3). RIP3 is related to RIP and RIP2 but does not posses a death domain or CARD motif at its C-terminus. RIP3 activates NF-Kappa B and potently induces apoptosis. RIP3 is expressed in a range of tissues including the spleen, liver, testis, heart, brain and lung.

Packaging

PBS, 0.02% sodium azide
+4°C or -20°C, Avoid repeated freezing and thawing.
For research use only.

About RIPK3 / RIP3

Q9Y572 NM_006871 NP_006862.2

RIPK3 Antibody, Receptor interacting protein 3 Antibody, RIP-like protein kinase 3 Antibody, RIP3 Antibody, RIP-3 Antibody, Receptor-interacting protein 3 Antibody

Essential for necroptosis, a programmed cell death process in response to death-inducing TNF-alpha family members. Upon induction of necrosis, RIPK3 interacts with, and phosphorylates RIPK1 and MLKL to form a necrosis-inducing complex. RIPK3 binds to and enhances the activity of three metabolic enzymes: GLUL, GLUD1, and PYGL. These metabolic enzymes may eventually stimulate the tricarboxylic acid cycle and oxidative phosphorylation, which could result in enhanced ROS production.

Immunohistochemistry

Immunohistochemistry
Immunohistochemistry of rat kidney with Rabbit anti-RIP3

Western blot

Western blot
Western blot of whole cell lysate from mouse 3T3 cells probed with Rabbit anti-RIP3 in the absence (A) or presence (B) of blocking peptide

Requested From: United States
Date Requested: 12/11/2016

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