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Anti-RIPK1 / RIP Antibody (C-Terminus) IHC-plus™ LS-B4701

Note: This antibody replaces LS-C114225
Catalog Size Price
LS-B4701-50 50 µg (1 mg/ml) Unavailable

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100% Guaranteed
Rabbit Polyclonal to Human RIPK1 / RIP
Human
IHC - Paraffin
Unconjugated

Details

Human RIPK1 / RIP
Rabbit
Human (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

IHC - Paraffin (5 µg/ml)

Specificity and Use

LS-E30062 - Liquid - 50 µg - $145.00
Immunizing peptide used to generate LS-B4701. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
C-Terminus

Packaging

PBS, 0.02% sodium azide.
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
For research use only.

About RIPK1 / RIP

Q13546 NM_003804 NP_003795.2

RIPK1 Antibody, Cell death protein RIP Antibody, Receptor interacting protein Antibody, RIP1 Antibody, RIP Antibody, RIP-1 Antibody, Protein kinase rip Antibody, Receptor-interacting protein 1 Antibody, Rinp Antibody

Serine-threonine kinase which transduces inflammatory and cell-death signals (programmed necrosis) following death receptors ligation, activation of pathogen recognition receptors (PRRs), and DNA damage. Upon activation of TNFR1 by the TNF-alpha family cytokines, TRADD and TRAF2 are recruited to the receptor. Phosphorylates DAB2IP at 'Ser-728' in a TNF-alpha-dependent manner, and thereby activates the MAP3K5-JNK apoptotic cascade.

Immunohistochemistry

Immunohistochemistry
Anti-RIPK1 /RIP antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4701 concentration 5 ug/ml.

Requested From: 
Date Requested: 10/19/2017

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