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RIC8A

RIC8 guanine nucleotide exchange factor A

Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins. Able to activate GNAI1, GNAO1 and GNAQ, but not GNAS by exchanging bound GDP for free GTP. Involved in regulation of microtubule pulling forces during mitotic movement of chromosomes by stimulating G(i)-alpha protein, possibly leading to release G(i)-alpha-GTP and NuMA proteins from the NuMA-GPSM2-G(i)-alpha-GDP complex By similarity. Also acts as an activator for G(q)-alpha (GNAQ) protein by enhancing the G(q)-coupled receptor-mediated ERK activation.

Gene Name: RIC8 guanine nucleotide exchange factor A
Synonyms: RIC8A, Protein Ric-8A, Synembryn, Synembryn-A, RIC8
Target Sequences: NM_021932 NP_068751.4 Q9NPQ8

☰ Filters
Antibodies (25)
Proteins (4)
Over-Expression Lysate (2)
Primary (25)
Recombinant (2)
RIC8A (29)
Human (25)
Mouse (9)
Rat (9)
Bovine (5)
Chimpanzee (3)
Dog (3)
Gibbon (3)
Guinea pig (3)
Horse (4)
Monkey (4)
Orangutan (3)
Pig (1)
Rabbit (4)
IHC (9)
IHC-P (4)
WB (20)
ELISA (12)
IF (2)
IP (2)
Peptide-ELISA (2)
rabbit (22)
mouse (2)
goat (1)
IgG (17)
IgG1 (2)
monoclonal mc (2)
polyclonal pc (23)
OTI3G3 (2)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (2)
Carrier-free (1)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (1)
Unconjugated (17)
aa244-272 (7)
aa143-192 (4)
aa1-50 (1)
aa418-468 (1)
aa478-537 (1)
aa528-537 (1)
No (29)
GST, N-terminus (1)
Myc-DDK (Flag) (3)
Human (3)
293T Cells (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
RIC8A Antibody - IHC of paraffin-embedded Kidney tissue using anti-RIC8A mouse monoclonal antibody. (Dilution 1:50).
Select
RIC8A Mouse anti-Human Monoclonal (OTI3G3) Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
RIC8A Antibody - IHC of paraffin-embedded Kidney tissue using anti-RIC8A mouse monoclonal antibody. (Dilution 1:50).
Select
RIC8A Mouse anti-Human Monoclonal (Carrier-free) (OTI3G3) Antibody
Human
IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
Select
RIC8A Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$341
Select
RIC8A Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$351
RIC8A Antibody - Immunohistochemistry of paraffin-embedded human kidney tissue at dilution of 1:100
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RIC8A Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
RIC8A Antibody - Immunohistochemistry of paraffin-embedded human kidney tissue at dilution of 1:100
Select
RIC8A Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
RIC8A Antibody - IHC of paraffin-embedded Adrenal cortical tumor using RIC8A antibody at 1:100 dilution.
Select
RIC8A Rabbit anti-Human Polyclonal (aa478-537) Antibody
Bovine, Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$450
RIC8A Antibody - Immunohistochemistry of paraffin-embedded Human brain tissue  using RIC8A Polyclonal Antibody at dilution of 1:55(×200)
Select
RIC8A Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
RIC8A Antibody - Immunohistochemistry of paraffin-embedded Human tonsil tissue  using RIC8A Polyclonal Antibody at dilution of 1:80(×200)
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RIC8A Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
Select
RIC8A Rabbit anti-Human Polyclonal (aa244-272) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
Select
RIC8A Rabbit anti-Human Polyclonal (aa244-272) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
RIC8A Rabbit anti-Human Polyclonal (aa244-272) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
Select
RIC8A Rabbit anti-Human Polyclonal (aa244-272) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
Select
RIC8A Rabbit anti-Human Polyclonal (aa244-272) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
Select
RIC8A Rabbit anti-Human Polyclonal (aa244-272) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
RIC8A Antibody - Detection of human and mouse Ric-8A by western blot. Samples: Whole cell lysate (50 µg) from HeLa, HEK293T, Jurkat, mouse TCMK-1, and mouse NIH 3T3 cells prepared using NETN lysis buffer. Antibodies: Affinity purified rabbit anti-Ric-8A antibody used for WB at 0.1 µg/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.
Select
RIC8A Rabbit anti-Human Polyclonal (aa418-468) Antibody
Mouse, Human
IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
RIC8A Antibody - Western blot analysis of extracts of HepG2 cells using RIC8A antibody. The lane on the left was treated with blocking peptide.
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RIC8A Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
RIC8A Antibody - Antibody staining (1 ug/ml) of human brain lysate (RIPA buffer, 35 ug total protein per lane). Primary incubated for 1 hour. Detected by Western blot of chemiluminescence.
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RIC8A Goat anti-Human Polyclonal (aa528-537) Antibody
Rabbit, Mouse, Bovine, Rat, Pig, Horse, Human, Monkey
Peptide-ELISA, WB
Unconjugated
100 µg/$503
RIC8A Antibody - RIC8A antibody Western blot of THP-1 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
RIC8A Rabbit anti-Human Polyclonal (aa143-192) Antibody
Human
WB
Unconjugated
100 µl/$424
RIC8A Antibody - RIC8A antibody Western blot of THP-1 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
RIC8A Rabbit anti-Human Polyclonal (aa143-192) (HRP) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Horse, Orangutan, Gibbon, Chimpanzee, Human, Monkey
WB
HRP Conjugated
100 µl/$469
RIC8A Antibody - RIC8A antibody Western blot of THP-1 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
RIC8A Rabbit anti-Human Polyclonal (aa143-192) (Biotin) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Horse, Orangutan, Gibbon, Chimpanzee, Human, Monkey
WB
Biotin Conjugated
100 µl/$469
RIC8A Antibody - RIC8A antibody Western blot of THP-1 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
RIC8A Rabbit anti-Human Polyclonal (aa143-192) (FITC) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Horse, Orangutan, Gibbon, Chimpanzee, Human, Monkey
WB
FITC Conjugated
100 µl/$469
RIC8A Antibody - RIC8A Antibody western blot of A2058 cell line lysates (35 ug/lane). The RIC8A antibody detected the RIC8A protein (arrow).
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RIC8A Rabbit anti-Human Polyclonal (aa244-272) Antibody
Human
WB
Unconjugated
400 µl/$393
RIC8A Antibody - Western blot analysis of extracts of various cell lines, using RIC8A antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 10s.
Select
RIC8A Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
Select
RIC8A Rabbit anti-Human Polyclonal (aa1-50) Antibody
Human
IP
Unconjugated
10 µg/$295; 100 µl/$514
Viewing 1-25 of 29 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).