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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Rhodopsin Kinase / GRK1 Antibody (clone 1G8) LS‑C198087
GRK1 antibody LS-C198087 is an unconjugated mouse monoclonal antibody to human GRK1 (Rhodopsin Kinase). Validated for ELISA and WB.
Catalog
Size
Price
LS-C198087-100
100 µg
Unavailable

Popular Rhodopsin Kinase / GRK1 Products

Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with GRK1 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Species: Human, Mouse
Applications: IHC, IHC - Paraffin, Western blot
IHC of paraffin-embedded human brain tissue, using GRK1 (Ab-21) Antibody. The picture on the right is treated with the synthesized peptide.
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
IHC of paraffin-embedded human brain, using GRK1 (Phospho-Ser21) Antibody. The sample on the right was incubated with synthetic peptide.
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Antibody
Species: Human, Mouse
Applications: IHC, Western blot, ELISA
Antibody
Species: Human, Mouse, Rat
Applications: IHC, Western blot, Immunoprecipitation, ELISA

Product Description

GRK1 antibody LS-C198087 is an unconjugated mouse monoclonal antibody to human GRK1 (Rhodopsin Kinase). Validated for ELISA and WB.
About Rhodopsin Kinase / GRK1
The G protein-coupled receptor kinases (GRKs) are important enzymes in the desensitization of activated G protein-coupled receptors (GPCR). Among these enzymes, GRK1 is involved in phototransduction and is the most specialized kinase of the family. GRK1 phosphorylates photoactivated rhodopsin (Rho*), initiating steps in its deactivation. GRK1 has been shown to be essential for normal deactivation of cone phototransduction. Q15835 NM_002929 NP_002920.1

GRK1 Antibody, GPRK1 Antibody, RK Antibody, Rhodopsin kinase Antibody, RHOK Antibody


Specifications

Target
Human Rhodopsin Kinase / GRK1
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG2b,k Monoclonal [1G8]
Conjugations
Unconjugated
Purification
Purified from ascites by Protein A
Modifications
Unmodified
Applications
  • Western blot
  • ELISA
Immunogen
GRK1 (NP_002920.1, aa51-150 partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human Rhodopsin Kinase / GRK1
Usage
Sandwich ELISA: Recombinant protein. Western Blot: Recombinant protein.
Presentation
PBS, pH 7.4
Storage
Store at -20°C or lower. Aliquot to avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Enzyme-Linked Immunosorbent Assay

Detection limit for recombinant GST tagged GRK1 is approximately 0.3 ng/ml as a capture antibody.
Detection limit for recombinant GST tagged GRK1 is approximately 0.3 ng/ml as a capture antibody.

Enzyme-Linked Immunosorbent Assay

Detection limit for recombinant GST tagged GRK1 is approximately 0.3 ng/ml as a capture antibody.
Detection limit for recombinant GST tagged GRK1 is approximately 0.3 ng/ml as a capture antibody.

Enzyme-Linked Immunosorbent Assay

Detection limit for recombinant GST tagged GRK1 is approximately 0.3 ng/ml as a capture antibody.
Detection limit for recombinant GST tagged GRK1 is approximately 0.3 ng/ml as a capture antibody.

Enzyme-Linked Immunosorbent Assay

Detection limit for recombinant GST tagged GRK1 is approximately 0.3 ng/ml as a capture antibody.
Detection limit for recombinant GST tagged GRK1 is approximately 0.3 ng/ml as a capture antibody.


Requested From: 
Date Requested: 6/19/2018

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