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RGS18

regulator of G-protein signaling 18

RGS18 is a member of the regulator of G-protein signaling family. This protein is contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.

Gene Name: regulator of G-protein signaling 18
Family/Subfamily: Regulator of G-protein signalling , not assigned-Regulator of G-protein signalling
Synonyms: RGS18
Target Sequences: NM_130782 NP_570138.1 Q9NS28

Publications (1)

1
A newly identified complex of spinophilin and the tyrosine phosphatase, SHP-1, modulates platelet activation by regulating G protein-dependent signaling. Ma P, Cierniewska A, Signarvic R, Cieslak M, Kong H, Sinnamon AJ, Neubig RR, Newman DK, Stalker TJ, Brass LF. Blood. 2012 119:1935-45. (IP; Human) [Full Text Article] [PubMed:22210881] [PMC:PMC3293648]

☰ Filters
Antibodies (19)
Proteins (4)
Over-Expression Lysate (2)
Primary (19)
Recombinant (2)
RGS18 (23)
Human (15)
Mouse (4)
Rat (6)
Bovine (3)
Chimpanzee (6)
Dog (3)
Gibbon (3)
Monkey (3)
Pig (3)
IHC (1)
IHC-P (1)
WB (15)
ELISA (4)
IF (1)
Peptide-ELISA (1)
rabbit (17)
mouse (1)
goat (1)
Product Group
IHCPlus (1)
IgG (8)
IgG1 (1)
monoclonal mc (1)
polyclonal pc (18)
OTI8C8 (1)
Biotin Conjugated (4)
FITC Conjugated (4)
HRP Conjugated (4)
Unconjugated (7)
N-Terminus (4)
aa120-169 (4)
aa41-90 (4)
aa221-235 (1)
aa30-48 (1)
No (23)
GST (1)
His, N-Terminal (1)
Myc-DDK (Flag) (2)
Human (3)
293T Cells (1)
E. coli (1)
HEK 293 Cells (1)
Wheat Germ Extract (1)
Purified (1)
RGS18 Antibody - Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)
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RGS18 Goat anti-Human Polyclonal (aa221-235) Antibody
Human
IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$460
RGS18 Antibody - Immunohistochemistry of paraffin-embedded human tonsil tissue using RGS18 Antibody at dilution of 1:100
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RGS18 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC
Unconjugated
50 µg/$294; 100 µg/$360
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RGS18 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
Select
RGS18 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
Select
RGS18 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
RGS18 Antibody - RGS18 antibody Western blot of Mouse Lung lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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RGS18 Rabbit anti-Mouse Polyclonal (aa41-90) Antibody
Mouse
WB
Unconjugated
100 µl/$424
RGS18 Antibody - RGS18 antibody Western blot of Mouse Lung lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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RGS18 Rabbit anti-Mouse Polyclonal (aa41-90) (HRP) Antibody
Mouse, Rat
WB
HRP Conjugated
100 µl/$469
RGS18 Antibody - RGS18 antibody Western blot of Mouse Lung lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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RGS18 Rabbit anti-Mouse Polyclonal (aa41-90) (Biotin) Antibody
Mouse, Rat
WB
Biotin Conjugated
100 µl/$469
RGS18 Antibody - RGS18 antibody Western blot of Mouse Lung lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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RGS18 Rabbit anti-Mouse Polyclonal (aa41-90) (FITC) Antibody
Mouse, Rat
WB
FITC Conjugated
100 µl/$469
RGS18 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY RGS18. (Right lane) cDNA for 48 hrs and lysed
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RGS18 Mouse anti-Human Monoclonal (OTI8C8) Antibody
Human
WB
Unconjugated
100 µl/$434
RGS18 Antibody - RGS18 antibody ARP42804_T100-NP_570138-RGS18(regulator of G-protein signalling 18) Antibody Western blot of Fetal Thymus lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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RGS18 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$397
RGS18 Antibody - RGS18 antibody ARP42804_T100-NP_570138-RGS18(regulator of G-protein signalling 18) Antibody Western blot of Fetal Thymus lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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RGS18 Rabbit anti-Human Polyclonal (N-Terminus) (HRP) Antibody
Dog, Bovine, Rat, Pig, Gibbon, Chimpanzee, Human, Monkey
WB
HRP Conjugated
100 µl/$442
RGS18 Antibody - RGS18 antibody ARP42804_T100-NP_570138-RGS18(regulator of G-protein signalling 18) Antibody Western blot of Fetal Thymus lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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RGS18 Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody
Dog, Bovine, Rat, Pig, Gibbon, Chimpanzee, Human, Monkey
WB
Biotin Conjugated
100 µl/$442
RGS18 Antibody - RGS18 antibody ARP42804_T100-NP_570138-RGS18(regulator of G-protein signalling 18) Antibody Western blot of Fetal Thymus lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
RGS18 Rabbit anti-Human Polyclonal (N-Terminus) (FITC) Antibody
Dog, Bovine, Rat, Pig, Gibbon, Chimpanzee, Human, Monkey
WB
FITC Conjugated
100 µl/$442
RGS18 Antibody - Western blot of RGS18 in 1) transfected 293T cells and 2) untransfected 293T cells using RGS18 Antibody at 1:500.
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RGS18 Rabbit anti-Human Polyclonal (aa30-48) Antibody
Human
WB
Unconjugated
100 µl/$386
RGS18 Antibody - RGS18 antibody Western blot of HepG2 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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RGS18 Rabbit anti-Human Polyclonal (aa120-169) Antibody
Human
WB
Unconjugated
100 µl/$424
RGS18 Antibody - RGS18 antibody Western blot of HepG2 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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RGS18 Rabbit anti-Human Polyclonal (aa120-169) (HRP) Antibody
Human, Chimpanzee
WB
HRP Conjugated
100 µl/$469
RGS18 Antibody - RGS18 antibody Western blot of HepG2 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
RGS18 Rabbit anti-Human Polyclonal (aa120-169) (Biotin) Antibody
Human, Chimpanzee
WB
Biotin Conjugated
100 µl/$469
RGS18 Antibody - RGS18 antibody Western blot of HepG2 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
RGS18 Rabbit anti-Human Polyclonal (aa120-169) (FITC) Antibody
Human, Chimpanzee
WB
FITC Conjugated
100 µl/$469
RGS18 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
27.4 kDa
20 µg/$150
RGS18 Protein - 12.5% SDS-PAGE of human RGS18 stained with Coomassie Blue
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Wheat Germ Extract
GST
51.59 kDa
10 µg/$479; 25 µg/$670
RGS18 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
27.4 kDa
100 µg/$494
RGS18 Protein
Select
E. coli
His, N-Terminal
27.6 kDa
50 µg/$419
Viewing 1-23 of 23 product results



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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).