Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone RET01] (IgG1) to Human RET
IHC - Paraffin
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [RET01]
Tissue culture supernatant
IHC - Paraffin (1:10 - 1:20)
Specificity and Use
RET antibody was raised against bALB/C mice were injected with recombinant protein encoding the extreme C-terminal cytoplasmic region of the human ret oncoprotein.
Ret proto-oncogene encodes a cell surface glycoprotein belonging to a member of the receptor tyrosine kinase family and is located on chromosome 10q11.2. Ret is observed in several regions of the central nervous system: in the developing cranial nerve ganglia, in a subset of cells within dorsal root ganglia, in motor neurons in the spinal cord, and in the hindbrain.
IHC-P requires HIER antigen retrieval in 10 mM citrate buffer pH 6.0.
RET Antibody, Cadherin family member 12 Antibody, CDHF12 Antibody, C-ret Antibody, Hirschsprung disease 1 Antibody, HSCR1 Antibody, Hydroxyaryl-protein kinase Antibody, Oncogene ret Antibody, Proto-oncogene c-Ret Antibody, RET-ELE1 Antibody, RET51 Antibody, Ret proto-oncogene Antibody, RET transforming sequence Antibody, RET43 Antibody, Men2-ret Antibody, MEN2B Antibody, MTC1 Antibody, Receptor tyrosine kinase Antibody, CDHR16 Antibody, MEN2A Antibody, PTC Antibody, RET9 Antibody
Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. Phosphorylates PTK2/FAK1. Regulates both cell death/survival balance and positional information.