Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human (tested or 100% immunogen sequence identity)
Monkey (at least 90% immunogen sequence identity)
Protein G purified
IHC - Paraffin
Specificity and Use
RET antibody was raised against synthetic peptide from human RET. Percent identity by BLAST analysis: Human (100%); Gorilla, Gibbon, Monkey, Marmoset (94%); Mouse, Rat, Pig (88%); Elephant, Panda, Bat, Rabbit (81%).
KLH conjugated synthetic peptide comprising amino acids 1078 - 1093 [TRADGTNTGFPRYPND] of the human ret proto-oncogene (RET) protein.
PBS, 0.09% sodium azide.
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
RET Antibody, Cadherin family member 12 Antibody, CDHF12 Antibody, C-ret Antibody, Hirschsprung disease 1 Antibody, HSCR1 Antibody, Hydroxyaryl-protein kinase Antibody, Oncogene ret Antibody, Proto-oncogene c-Ret Antibody, RET-ELE1 Antibody, RET51 Antibody, Ret proto-oncogene Antibody, RET transforming sequence Antibody, RET43 Antibody, Men2-ret Antibody, MEN2B Antibody, MTC1 Antibody, Receptor tyrosine kinase Antibody, CDHR16 Antibody, MEN2A Antibody, PTC Antibody, RET9 Antibody
Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. Phosphorylates PTK2/FAK1. Regulates both cell death/survival balance and positional information.