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Human RCHY1 / PIRH2 | |
Rabbit | |
Human, Monkey, Mouse (tested or 100% immunogen sequence identity) | |
IgG Polyclonal | |
Unconjugated | |
Affinity purified | |
Unmodified |
RCHY1 / PIRH2 antibody was raised against synthetic peptide corresponding to residues near the carboxy terminus of human RCHY1 protein isoform1. | |
C-Terminus | |
Endogenous levels of total human RCHY1. Species Crossreactivity: monkey, mouse. | |
Western Blot: 1:1000. Incubate membrane with diluted antibody in 5% BSA, 1X TBS,. 0.1% Tween-20 at 4°C with gentle shaking, overnight. |
10 mM sodium HEPES, pH 7.5, 150 mM sodium chloride, 100ug/ml BSA, 50% glycerol | |
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. | |
For research use only. |
RCHY1 Antibody, ARNIP Antibody, CHIMP Antibody, HARNIP Antibody, HPirh2 Antibody, PIRH2E Antibody, PIRH2 Antibody, PIRH2F Antibody, PRO1996 Antibody, RING finger protein 199 Antibody, Zinc finger protein 363 Antibody, ZNF363 Antibody, p53-induced RING-H2 protein Antibody, RNF199 Antibody
Mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including p53/TP53, P73, HDAC1 and CDKN1B. Preferentially acts on tetrameric p53/TP53. Monoubiquitinates the translesion DNA polymerase POLH. Contributes to the regulation of the cell cycle progression. Increases AR transcription factor activity.