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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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RCC1 Antibody (phospho‑Ser11) LS‑C131814
Antibody
RCC1 antibody LS-C131814 is an unconjugated rabbit polyclonal antibody to RCC1 from human and monkey. Validated for WB.
Catalog
Size
Price
LS-C131814-100
100 µl
Unavailable

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Product Description

RCC1 antibody LS-C131814 is an unconjugated rabbit polyclonal antibody to RCC1 from human and monkey. Validated for WB.
About RCC1
Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP. Involved in the regulation of onset of chromosome condensation in the S phase. Binds both to the nucleosomes and double-stranded DNA. RCC1-Ran complex (together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA. Plays a key role in nucleo-cytoplasmic transport, mitosis and nuclear-envelope assembly. P18754 NM_001269 NP_001260.1

RCC1 Antibody, Cell cycle regulatory protein Antibody, Chromosome condensation 1 Antibody, RCC1-I Antibody, SNHG3-RCC1 Antibody, CHC1 Antibody


Specifications

Target
Human RCC1
Host
Rabbit
Reactivity
Human, Monkey (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Protein A purified
Modifications
Unmodified
Applications
  • Western blot (1:1000)
Immunogen
RCC1 antibody was raised against synthetic phosphopeptide corresponding to residues surrounding Ser11 of human RCC1 protein(KLH-coupled).
Epitope
pSer11
Specificity
Recognizes human Phospho-RCC1when phosphorylated at Ser11. Species cross-reactivity: monkey.
Usage
Suitable for use in Western blot: 1:1000. Incubate membrane with diluted antibody in 5% w/v BSA, 1X TBS, 0.1%. Tween-20 at 4°C with gentle shaking, overnight.
Presentation
10 mM HEPES, pH 7.5, 150 mM sodium chloride, 0.1 mg/ml BSA, 50% glycerol
Storage
May be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least1 year at -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/19/2018

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