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Anti-RCAN1 / DSCR1 Antibody (aa145-157) LS-C154834

Catalog Size Price
LS-C154834-100 100 µg (0.5 mg/ml) Unavailable

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Anti-RCAN1 / DSCR1 Antibody (aa145-157) LS-C154834
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100% Guaranteed
Goat Polyclonal to Human RCAN1 / DSCR1
Human, Monkey, Mouse, Rat, Bovine, Dog, Guinea pig, Hamster, Horse, Rabbit, Sheep, Chicken
Western blot, ELISA


Human RCAN1 / DSCR1
Human, Monkey, Mouse, Rat, Bovine, Dog, Guinea pig, Hamster, Horse, Rabbit, Sheep, Chicken (tested or 100% immunogen sequence identity)
Immunoaffinity purified


  • Western blot (1 - 3 µg/ml)
  • ELISA (1:32000)

Specificity and Use

RCAN1 / DSCR1 antibody was raised against synthetic peptide C-HIGSSHLAPPNPD from an internal region of human RCAN1 (NP_004405.3; NP_981962.1; NP_981963.1). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Galago, Marmoset, Mouse, Rat, Sheep, Dog, Bovine, Hamster, Elephant, Panda, Horse, Rabbit, Porcine, Guinea pig, Turkey, Chicken (100%); Platypus (92%); Xenopus (85%).
LS-E27598 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C154834. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Human RCAN1. This antibody is expected to recognize all three reported isoforms (NP_004405.3; NP_981962.1; NP_981963.1).
Peptide ELISA: antibody detection limit dilution 1:32000. Western blot: Approx 40kD band corresponding to isoform 1L observed in Mouse Brain lysates and this band is not present in the KO mouse. Additional bands around 55kD were consistently observed, however these band were also observed in the KO mice and therefore they represent non-specific signal. We call for caution when used for other assays than Western blot. Data kindly provided by Dana Crawford, PhD, Albany Medical College, NY, USA. Recommended concentration: 1-3 ug/ml.


Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Store at -20°C. Avoid freeze-thaw cycles.
For research use only.

About RCAN1 / DSCR1

P53805 NM_004414 NP_004405.3

RCAN1 Antibody, ADAPT78 Antibody, DSCR1 Antibody, MCIP1 Antibody, Regulator of calcineurin 1 Antibody, Calcipressin-1 Antibody, CSP1 Antibody, Near DSCR proline-rich protein Antibody

RCAN1 / DSCR1 interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Alternative splicing results in multiple transcript variants.

Western blot

Western blot
RCAN1 antibody (1 ug/ml) staining of Mouse Brain and KO Mouse Brain lysates (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Requested From: 
Date Requested: 3/24/2018

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