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Anti-RBL1 / p107 Antibody (aa143-192) LS-C112339

Catalog Size Price
LS-C112339-50 50 µg Unavailable

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39 RBL1 / p107 Antibodies

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Anti-RBL1 / p107 Antibody (phospho-Ser975) LS-C328486
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Anti-RBL1 / p107 Antibody (Internal) LS-C354458
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Western blot Image
Anti-RBL1 / p107 Antibody (aa310-390) LS-C385258
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100% Guaranteed
Rabbit Polyclonal to Human RBL1 / p107
Human, Mouse, Bat, Bovine, Dog, Horse, Pig
Western blot (applications tested for the base form of this product only)
Unconjugated

Details

Human RBL1 / p107
Rabbit
Human, Mouse, Bat, Bovine, Dog, Horse, Pig (tested or 100% immunogen sequence identity)
Rat, Guinea pig, Rabbit (at least 90% immunogen sequence identity)
Polyclonal
Unconjugated. Also available conjugated with Biotin, FITC, HRP.
Immunoaffinity purified
Unmodified

Applications

  • Western blot (0.2 - 1 µg/ml)
  • (applications tested for the base form of this product only)

Specificity and Use

RBL1 / p107 antibody was raised against synthetic peptide located between aa143-192 of human RBL1 (P28749-2, NP_899662). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Mouse, Bovine, Bat, Horse, Pig (100%); Galago, Rat, Elephant, Panda, Rabbit, Opossum, Guinea pig (92%); Marmoset, Dog, Xenopus (85%).
LS-E10799 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C112339. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
aa143-192
Human RBL1 / p107
Western Blot: Suggested dilution at 1 ug/ml in 5% skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody.

Packaging

Lyophilized
Distilled water
Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year); Short term (less than one week): +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

About RBL1 / p107

P28749 NM_002895 NP_002886.2

RBL1 Antibody, Cellular protein 107 Antibody, CP107 Antibody, p107 Antibody, Retinoblastoma-like 1 (p107) Antibody, Retinoblastoma-like protein 1 Antibody

Key regulator of entry into cell division. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases SUV420H1 and SUV420H2, leading to epigenetic transcriptional repression. Controls histone H4 'Lys-20' trimethylation. Probably acts as a transcription repressor by recruiting chromatin-modifying enzymes to promoters.

Western blot

Western blot
RBL1 / p107 antibody LS-C112339 Western blot of COLO205 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Requested From: 
Date Requested: 8/16/2017

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