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RBBP4 / RBAP48

retinoblastoma binding protein 4

Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the chromatin assembly factor 1 (CAF-1) complex, which is required for chromatin assembly following DNA replication and DNA repair; the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression; the nucleosome remodeling and histone deacetylase complex (the NuRD complex), which promotes transcriptional repression by histone deacetylation and nucleosome remodeling; the PRC2/EED-EZH2 complex, which promotes repression of homeotic genes during development; and the NURF (nucleosome remodeling factor) complex.

Gene Name: retinoblastoma binding protein 4
Synonyms: RBBP4, CAF-I p48, CAF-1 subunit C, CAF-I 48 kDa subunit, MSI1 protein homolog, Histone-binding protein RBBP4, NURF55, RBBP-4, RBAP48
Target Sequences: NM_005610 NP_005601.1 Q09028

Publications (2)

1
Metastasis tumor antigen 2 (MTA2) is involved in proper imprinted expression of H19 and Peg3 during mouse preimplantation development. Ma P, Lin S, Bartolomei MS, Schultz RM. Biology of reproduction. 2010 83:1027-35. (WB) [PubMed:20720167] [PMC:PMC2994328]
2
Phospho-?Np63a/microRNA network modulates epigenetic regulatory enzymes in squamous cell carcinomas. Ratovitski EA. Cell cycle (Georgetown, Tex.). 2014 13:749-61. (WB; Human) [Full Text Article] [PubMed:24394434] [PMC:PMC3979911] Related Antibodies: LS-C53331.

☰ Filters
Antibodies (36)
Proteins (6)
ELISA Kits (1)
Over-Expression Lysate (2)
Primary (36)
Recombinant (4)
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RBBP4 / RBAP48 (43)
Human (35)
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Rat (14)
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Chimpanzee (6)
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Horse (8)
Monkey (5)
Orangutan (3)
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IHC (20)
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rabbit (28)
mouse (8)
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RBBP4 / RBAP48 Antibody - Anti-RBBP4 / RBAP48 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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RBBP4 / RBAP48 Mouse anti-Human Monoclonal (aa1-425) (11G10) Antibody
Mouse, Human
IF, IHC, IHC-P, IP, WB
Unconjugated
50 µl/$460
RBBP4 / RBAP48 Antibody - Anti-RBBP4 / RBAP48 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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RBBP4 / RBAP48 Mouse anti-Human Monoclonal (2D7) Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$460
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RBBP4 / RBAP48 Mouse anti-Human Monoclonal (aa1-425) (4H9) Antibody
Human
IP, WB
Unconjugated
50 µg/$593
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RBBP4 / RBAP48 Mouse anti-Human Monoclonal (aa1-425) (15G12) Antibody
Human
IF, IP, WB
Unconjugated
100 µl/$450
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RBBP4 / RBAP48 Mouse anti-Human Monoclonal (aa1-425) (3-255) Antibody
Human
IF, IP, WB
Unconjugated
100 µg/$563
RBBP4 / RBAP48 Antibody - Immunohistochemical analysis of RbAp48 staining in mouse lung formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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RBBP4 / RBAP48 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ChrIP, ICC, IF, IHC, IHC-P, IP, WB
Unconjugated
50 µl/$286; 100 µl/$321; 200 µl/$386
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RBBP4 / RBAP48 Mouse anti-Human Monoclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$371
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RBBP4 / RBAP48 Rabbit anti-Human Polyclonal Antibody
Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$412
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RBBP4 / RBAP48 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$351
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RBBP4 / RBAP48 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$341
RBBP4 / RBAP48 Antibody - Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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RBBP4 / RBAP48 Rabbit anti-Human Polyclonal (aa71-120) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
RBBP4 / RBAP48 Antibody - Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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RBBP4 / RBAP48 Rabbit anti-Human Polyclonal (aa71-120) (HRP) Antibody
Xenopus, Chicken, Zebrafish, Pig, Horse, Bat, Bovine, Rabbit, Mouse, Dog, Guinea pig, Rat, Human, Monkey, Gibbon, Orangutan, Chimpanzee
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
RBBP4 / RBAP48 Antibody - Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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RBBP4 / RBAP48 Rabbit anti-Human Polyclonal (aa71-120) (Biotin) Antibody
Xenopus, Chicken, Zebrafish, Pig, Horse, Bat, Bovine, Rabbit, Mouse, Dog, Guinea pig, Rat, Human, Monkey, Gibbon, Orangutan, Chimpanzee
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
RBBP4 / RBAP48 Antibody - Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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RBBP4 / RBAP48 Rabbit anti-Human Polyclonal (aa71-120) (FITC) Antibody
Xenopus, Chicken, Zebrafish, Pig, Horse, Bat, Bovine, Rabbit, Mouse, Dog, Guinea pig, Rat, Human, Monkey, Gibbon, Orangutan, Chimpanzee
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
RBBP4 / RBAP48 Antibody
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RBBP4 / RBAP48 Rabbit anti-Human Polyclonal Antibody
Xenopus, Chicken, Zebrafish, Pig, Mouse, Dog, Guinea pig, Bovine, Bat, Rat, Human, Monkey
ICC, IHC, IHC-P, WB
Unconjugated
100 µl/$423
RBBP4 / RBAP48 Antibody
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RBBP4 / RBAP48 Rabbit anti-Human Polyclonal Antibody
Chicken, Bovine, Rabbit, Mouse, Dog, Guinea pig, Rat, Pig, Horse, Bat, Human, Monkey
ICC, IHC, IHC-P, IP, WB
Unconjugated
100 µl/$423
RBBP4 / RBAP48 Antibody - RbAp48 antibody IHC-paraffin. IHC(P): Mouse Liver Tissue.
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RBBP4 / RBAP48 Rabbit anti-Human Polyclonal (aa395-425) Antibody
Chicken, Sheep, Bovine, Rabbit, Mouse, Dog, Guinea pig, Rat, Pig, Horse, Bat, Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
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RBBP4 / RBAP48 Rabbit anti-Human Polyclonal Antibody
Human
IHC, IHC-P, IP, WB
Unconjugated
50 µl/$317; 100 µl/$375; 200 µl/$473
RBBP4 / RBAP48 Antibody
Select
RBBP4 / RBAP48 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µg/$575
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RBBP4 / RBAP48 Mouse anti-Human Monoclonal (aa1-425) (1D11) Antibody
Human
IF, IP, WB
Unconjugated
100 µg/$563
RBBP4 / RBAP48 Antibody - Detection of Human RBBP4/RbAp48 by Immunohistochemistry. Sample: FFPE section of human Ewing sarcoma. Antibody: Affinity purified rabbit anti-RBBP4/RbAp48 used at a dilution of 1:200 (1 ug/ml). Detection: DAB.
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RBBP4 / RBAP48 Rabbit anti-Human Polyclonal (aa1-50) Antibody
Mouse, Human
IHC, IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
RBBP4 / RBAP48 Antibody - Western blot analysis of extracts of various cell lines, using RBBP4 antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking.
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RBBP4 / RBAP48 Rabbit anti-Human Polyclonal Antibody
Human
ChrIP, IF, WB
Unconjugated
20 µl/$287; 50 µl/$341; 100 µl/$431; 200 µl/$539
RBBP4 / RBAP48 Antibody - 1:100 staining mouse brain tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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RBBP4 / RBAP48 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
RBBP4 / RBAP48 Antibody - Western blot of extracts of various cell lines, using RBBP4 antibody.
Select
RBBP4 / RBAP48 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
50 µl/$391; 100 µl/$489
RBBP4 / RBAP48 Antibody - IHC analysis of RbAp48 using anti-RbAp48 antibody. RbAp48 was detected in paraffin-embedded section of human intestinal cancer tissue. Heat mediated antigen retrieval was performed in citrate buffer (pH6, epitope retrieval solution) for 20 mins. The tissue section was blocked with 10% goat serum. The tissue section was then incubated with 2µg/ml mouse anti-RbAp48 antibody overnight at 4°C. Biotinylated goat anti-mouse IgG was used as secondary antibody and incubated for 30 minutes at 37°C. The tissue section was developed using Strepavidin-Biotin-Complex (SABC) with DAB as the chromogen.
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RBBP4 / RBAP48 Mouse anti-Human Monoclonal Antibody
Mouse, Rat, Human
IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
Viewing 1-25 of 43 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).