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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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RB1 / Retinoblastoma / RB Antibody LS‑C51764
Antibody
RB antibody LS-C51764 is an unconjugated mouse monoclonal antibody to RB (RB1 / Retinoblastoma) from human, mouse and rat. Validated for IHC, IP and WB.
Catalog
Size
Price
LS-C51764-50
50 µg (0.1 mg/ml)
Unavailable

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Product Description

RB antibody LS-C51764 is an unconjugated mouse monoclonal antibody to RB (RB1 / Retinoblastoma) from human, mouse and rat. Validated for IHC, IP and WB.
About RB1 / Retinoblastoma / RB
Key regulator of entry into cell division that acts as a tumor suppressor. Promotes G0-G1 transition when phosphorylated by CDK3/cyclin-C. Acts as a transcription repressor of E2F1 target genes. The underphosphorylated, active form of RB1 interacts with E2F1 and represses its transcription activity, leading to cell cycle arrest. P06400 NM_000321 NP_000312.2

RB1 Antibody, p105-Rb Antibody, Osteosarcoma Antibody, PRb Antibody, Retinoblastoma Antibody, Retinoblastoma 1 Antibody, OSRC Antibody, RB Antibody, Pp110 Antibody


Specifications

Target
Human RB1 / Retinoblastoma / RB
Host
Mouse
Reactivity
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal
Conjugations
Unconjugated
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin
  • Western blot (1:100)
  • Immunoprecipitation
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Human recombinant full length Rb protein.
Specificity
Rb of mouse, rat, and human
Presentation
PBS, 0.1% sodium azide, 0.2% gelatin.
Storage
Store at 4°C. Do not freeze.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/19/2018

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