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Anti-RAPGEF3 / EPAC Antibody (N-Terminus) IHC-plus™ LS-B9589

Note: This antibody replaces LS-C144466

Ordering

Wt. Vol. Conc. Price
50 µg - 1 mg/ml $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

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Rabbit Polyclonal to Human RAPGEF3 / EPAC
Human, Mouse, Rat
IHC - Paraffin, Immunofluorescence, Western blot, ELISA
Unconjugated

Details

Human RAPGEF3 / EPAC
Rabbit
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • IHC - Paraffin (5 µg/ml)
  • Immunofluorescence (20 µg/ml)
  • Western blot (1 µg/ml)
  • ELISA

Specificity and Use

RAPGEF3 / EPAC antibody was raised against an 18 amino acid peptide near the amino terminus of human EPAC1
LS-E31211 - Liquid - 50 µg - $145.00
N-Terminus
Human RAPGEF3 / EPAC. At least two isoforms of EPAC1 are known to exist; this antibody will detect both isoforms. EPAC1 antibody is predicted to not cross-react with EPAC2.

Packaging

PBS, 0.02% sodium azide
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
For research use only.

About RAPGEF3 / EPAC

O95398 NM_006105 NP_006096.2

RAPGEF3 Antibody, Bcm910 Antibody, CAMP-GEFI Antibody, CGEF1 Antibody, HSU79275 Antibody, EPAC Antibody, EPAC 1 Antibody, EPAC1 Antibody

Guanine nucleotide exchange factor (GEF) for RAP1A and RAP2A small GTPases that is activated by binding cAMP. Through simultaneous binding of PDE3B to RAPGEF3 and PIK3R6 is assembled in a signaling complex in which it activates the PI3K gamma complex and which is involved in angiogenesis. Plays a role in the modulation of the cAMP-induced dynamic control of endothelial barrier function through a pathway that is independent on Rho-mediated signaling.

Immunohistochemistry

Immunohistochemistry
Anti-RAPGEF3 / EPAC antibody IHC staining of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B9589 concentration 5 ug/ml.

Immunofluorescence

Immunofluorescence
Immunofluorescence of EPAC1 in rat brain tissue with EPAC1 antibody at 20 µg/mL.

Western blot

Western blot
Western blot analysis of EPAC1 in rat skeletal muscle tissue lysate with EPAC1 antibody at 1 ug/ml.
 

Requested From: United States
Date Requested: 12/10/2016

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