Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human, Monkey (tested or 100% immunogen sequence identity)
IHC - Paraffin (3.75 µg/ml)
Western blot (0.1 - 1 µg/ml)
Specificity and Use
RANBP1 antibody was raised against synthetic peptide C-LSVKEETKEDAEEKQ from the C-terminus of human RANBP1 (NP_002873.1). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%); Marmoset (87%).
LS-E25741 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-B9188. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
RANBP1 Antibody, RAN binding protein 1 Antibody, Ran-binding protein 1 Antibody, HTF9A Antibody
Ran/TC4-binding protein, RanBP1, interacts specifically with GTP-charged RAN. RANBP1 encodes a 23-kD protein that binds to RAN complexed with GTP but not GDP. RANBP1 does not activate GTPase activity of RAN but does markedly increase GTP hydrolysis by the RanGTPase-activating protein (RanGAP1). The RANBP1 cDNA encodes a 201-amino acid protein that is 92% similar to its mouse homolog.