Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone 4D1] (IgG2a,k) to Human RALB
IHC - Paraffin, Western blot, Immunoprecipitation, ELISA
Human (tested or 100% immunogen sequence identity)
IgG2a,k Monoclonal [4D1]
Purified from ascites by Protein A
IHC - Paraffin (5 µg/ml)
Western blot (1:500 - 1:1000)
Specificity and Use
RALB antibody was raised against rALB (AAH18163, 89 a.a. ~ 183 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Immunohistochemistry: Formalin-fixed paraffin-embedded sections. Sandwich ELISA: Recombinant protein. Western Blot using transfected cell line lysates and the recombinant protein used as the immunogen.
PBS, pH 7.4
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
RALB Antibody, GTP binding protein) Antibody, RAS-like protein B Antibody, Ras-related protein Ral-B Antibody
Multifunctional GTPase involved in a variety of cellular processes including gene expression, cell migration, cell proliferation, oncogenic transformation and membrane trafficking. Accomplishes its multiple functions by interacting with distinct downstream effectors. Acts as a GTP sensor for GTP-dependent exocytosis of dense core vesicles. Required both to stabilize the assembly of the exocyst complex and to localize functional exocyst complexes to the leading edge of migrating cells.