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Anti-RAD9A / RAD9 Antibody (aa1125-1139) LS-C42615

Catalog Size Price
LS-C42615-50 50 µg (0.5 mg/ml) Unavailable

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100% Guaranteed
Rabbit Polyclonal (IgG) to Yeast RAD9A / RAD9
Western blot, ELISA


Yeast RAD9A / RAD9
Yeast (tested or 100% immunogen sequence identity)
IgG Polyclonal


  • Western blot (1:50 - 1:250)
  • ELISA (1:2000 - 1:4000)

Specificity and Use

RAD9A / RAD9 antibody was raised against synthetic peptide corresponding to aa 1125-1139 of yeast Rad9 protein conjugated to Keyhole Limpet Hemocyanin (KLH).
Detects Saccharomyces cerevisiae Rad9, a protein involved in the DNA damage checkpoint. In S. cerevisiae this checkpoint is mainly controlled by the PI(3) kinase-like kinase (PIKK) Mec1, which is activated in response to DNA damage. Activated Mec1 hyperphosphorylates Rad9, which in turn triggers the binding of Rad53, the ortholog of mammalian Chk2. Activated Rad53 specifically targets substrates required for cell cycle arrest, gene expression and efficient DNA repair. Mutations affecting Rad9 impair checkpoint induced cell-cycle arrest and increase genomic instability. Is pan reactive with both the phosphorylated and non-phosphorylated forms of this protein.
Western Blot: LS-C42615 detects a band of approximately 60kD.


PBS, pH 7.2, 0.01% sodium azide.
For research use only.

About RAD9A / RAD9

Q99638 NM_004584 NP_004575.1

RAD9A Antibody, HRAD9 Antibody, RAD9 Antibody, RAD9 homolog Antibody, RAD9 (S. pombe) homolog Antibody, RAD9 homolog A (S. pombe) Antibody

Component of the 9-1-1 cell-cycle checkpoint response complex that plays a major role in DNA repair. The 9-1-1 complex is recruited to DNA lesion upon damage by the RAD17-replication factor C (RFC) clamp loader complex. Acts then as a sliding clamp platform on DNA for several proteins involved in long-patch base excision repair (LP-BER).

Requested From: 
Date Requested: 3/22/2018

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