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RAD51B

RAD51 paralog B

Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents. May promote the assembly of presynaptic RAD51 nucleoprotein filaments. Binds single-stranded DNA and double-stranded DNA and has DNA-dependent ATPase activity. Part of the RAD21 paralog protein complex BCDX2 which acts in the BRCA1-BRCA2-dependent HR pathway. Upon DNA damage, BCDX2 acts downstream of BRCA2 recruitment and upstream of RAD51 recruitment. BCDX2 binds predominantly to the intersection of the four duplex arms of the Holliday junction and to junction of replication forks. The BCDX2 complex was originally reported to bind single-stranded DNA, single-stranded gaps in duplex DNA and specifically to nicks in duplex DNA. The BCDX2 subcomplex RAD51B:RAD51C exhibits single-stranded DNA-dependent ATPase activity suggesting an involvement in early stages of the HR pathway.

Gene Name: RAD51 paralog B
Synonyms: RAD51B, HREC2, RAD51-like 1 (S. cerevisiae), RAD51L1, RAD51-like protein 1, Recombination repair protein, REC2, RecA-like protein, R51H2, RAD51 (S. cerevisiae)-like 1, RAD51 homolog B
Target Sequences: NM_002877 NP_002868.1 O15315

Publications (1)

1
Dysfunctional homologous recombination mediates genomic instability and progression in myeloma. Shammas MA, Shmookler Reis RJ, Koley H, Batchu RB, Li C, Munshi NC. Blood. 2009 113:2290-7. [PubMed:19050310] [PMC:PMC2652372]

☰ Filters
Antibodies (22)
Proteins (5)
Over-Expression Lysate (2)
Primary (22)
Recombinant (3)
RAD51B (27)
Human (21)
Mouse (10)
Rat (1)
Bovine (3)
Chimpanzee (6)
Dog (3)
Gibbon (3)
Guinea pig (3)
Monkey (9)
Primate (1)
Rabbit (3)
IHC (10)
IHC-P (6)
WB (19)
Flo (2)
ELISA (4)
IF (5)
Peptide-ELISA (3)
rabbit (17)
mouse (4)
goat (1)
Product Group
IHCPlus (1)
IgG (9)
IgG1 (2)
monoclonal mc (4)
polyclonal pc (18)
1 H3/13 (1)
OTI7H4 (2)
Biotin Conjugated (2)
Carrier-free (1)
FITC Conjugated (2)
HRP Conjugated (2)
Unconjugated (16)
aa143-192 (4)
aa251-300 (4)
180-260 aa, Internal (1)
Gly226 (1)
aa119-346 (1)
aa2-14 (1)
aa201-250 (1)
No (27)
GST (1)
His (1)
His, N-Terminal (1)
Myc-DDK (Flag) (2)
Human (4)
293T Cells (1)
E. coli (2)
HEK 293 Cells (1)
Wheat Germ Extract (1)
Purified (2)
RAD51B Antibody - Anti-RAD51L1 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY RAD51L1.
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RAD51B Mouse anti-Human Monoclonal (OTI7H4) Antibody
Human
Flo, IF, WB
Unconjugated
100 µl/$434
RAD51B Antibody - Anti-RAD51L1 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY RAD51L1.
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RAD51B Mouse anti-Human Monoclonal (aa119-346) (Carrier-free) (OTI7H4) Antibody
Human
Flo, IF, WB
Unconjugated, Carrier-free
100 µg/$511
RAD51B Antibody - Anti-RAD51B antibody IHC staining of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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RAD51B Rabbit anti-Human Polyclonal (aa143-192) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
RAD51B Antibody - Anti-RAD51B antibody IHC staining of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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RAD51B Rabbit anti-Human Polyclonal (aa143-192) (HRP) Antibody
Rabbit, Dog, Guinea pig, Human, Monkey, Chimpanzee, Gibbon
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
RAD51B Antibody - Anti-RAD51B antibody IHC staining of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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RAD51B Rabbit anti-Human Polyclonal (aa143-192) (Biotin) Antibody
Rabbit, Dog, Guinea pig, Human, Monkey, Chimpanzee, Gibbon
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
RAD51B Antibody - Anti-RAD51B antibody IHC staining of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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RAD51B Rabbit anti-Human Polyclonal (aa143-192) (FITC) Antibody
Rabbit, Dog, Guinea pig, Human, Monkey, Chimpanzee, Gibbon
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
RAD51B Antibody - Immunohistochemistry analysis of paraffin-embedded human pancreas tissue, using RAD51L1 Antibody. The picture on the right is blocked with the synthesized peptide.
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RAD51B Rabbit anti-Human Polyclonal (aa201-250) Antibody
Mouse, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
RAD51B Antibody - Rad51L1 Antibody (1 H3/13) - Western blot of Rad51L1 expression in 1) HeLa, 2) HepG2 and 3) Cos 7 whole cell lysates.
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RAD51B Mouse anti-Human Monoclonal (1 H3/13) Antibody
Human, Primate
WB
Unconjugated
0.1 ml/$386
RAD51B Antibody - 1:100 staining human brain tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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RAD51B Rabbit anti-Human Polyclonal Antibody
Mouse, Human, Monkey
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
RAD51B Antibody - Immunofluorescence analysis of GFP-RNF168 trangenic U2OS cells.
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RAD51B Rabbit anti-Human Polyclonal Antibody
Mouse, Rat
IF, IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
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RAD51B Rabbit anti-Human Polyclonal (180-260 aa, Internal) Antibody
Mouse, Human, Monkey
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
RAD51B Antibody - Peptide - + Immunohistochemistry analysis of paraffin-embedded human pancreas tissue using RAD51L1 antibody.
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RAD51B Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
100 µg/$357
RAD51B Antibody - IHC of Rad51B (G226) pAb in paraffin-embedded human pancreas tissue.
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RAD51B Rabbit anti-Human Polyclonal (Gly226) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$321; 100 µl/$403
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RAD51B Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$341
Select
RAD51B Rabbit anti-Human Polyclonal Antibody
Human
IF
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
Select
RAD51B Mouse anti-Human Monoclonal Antibody
Human
ELISA
Unconjugated
100 µl/$649
Select
RAD51B Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
RAD51B Antibody - RAD51L1 antibody Western blot of COLO205 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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RAD51B Rabbit anti-Human Polyclonal (aa251-300) Antibody
Human
WB
Unconjugated
100 µl/$424
RAD51B Antibody - RAD51L1 antibody Western blot of COLO205 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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RAD51B Rabbit anti-Human Polyclonal (aa251-300) (HRP) Antibody
Mouse, Bovine, Human, Monkey, Chimpanzee
WB
HRP Conjugated
100 µl/$469
RAD51B Antibody - RAD51L1 antibody Western blot of COLO205 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
RAD51B Rabbit anti-Human Polyclonal (aa251-300) (Biotin) Antibody
Mouse, Bovine, Human, Monkey, Chimpanzee
WB
Biotin Conjugated
100 µl/$469
RAD51B Antibody - RAD51L1 antibody Western blot of COLO205 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
RAD51B Rabbit anti-Human Polyclonal (aa251-300) (FITC) Antibody
Mouse, Bovine, Human, Monkey, Chimpanzee
WB
FITC Conjugated
100 µl/$469
Select
RAD51B Goat anti-Human Polyclonal (aa2-14) Antibody
Human, Monkey
Peptide-ELISA
Unconjugated
100 µg/$384
RAD51B Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
42 kDa
100 µg/$494
RAD51B Protein
Select
E. coli
His, N-Terminal
42 kDa
50 µg/$419
RAD51B Protein - 12.5% SDS-PAGE of human RAD51L1 stained with Coomassie Blue
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Wheat Germ Extract
GST
68.6 kDa
10 µg/$479; 25 µg/$670
Viewing 1-25 of 27 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).