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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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RAD50 Antibody (C‑Terminus) LS‑C2861
RAD50 antibody LS-C2861 is an unconjugated rabbit polyclonal antibody to RAD50 from human, mouse and hamster. Validated for IP and WB.
Catalog
Size
Price
LS-C2861-100
100 µl
$335

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Product Description

RAD50 antibody LS-C2861 is an unconjugated rabbit polyclonal antibody to RAD50 from human, mouse and hamster. Validated for IP and WB.

Specifications

Target
Human RAD50
Synonyms
RAD50, DNA repair protein RAD50, HRad50, NBSLD, RAD50 (S. cerevisiae) homolog, RAD50 homolog (S. cerevisiae), RAD502, RAD50-2
Host
Rabbit
Reactivity
Human, Mouse, Hamster (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Antiserum
Modifications
Unmodified
Applications
  • Western blot (1:2000)
  • Immunoprecipitation
Immunogen
RAD50 antibody was raised against c-terminal mRad50 protein (604 amino acids)
Epitope
C-Terminus
Specificity
Rad50.
Presentation
Serum, 0.02% Sodium Azide
Storage
Short term: 4°C; Long term: -70°C.
Restrictions
For research use only.
About RAD50
Component of the MRN complex, which plays a central role in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity and meiosis. The complex possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity, which are provided by MRE11A. RAD50 may be required to bind DNA ends and hold them in close proximity. Q92878 NM_005732 NP_005723.2


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Images

Western blot

RAD50 Antibody - WB detection of Rad50 in HeLa nuclear extracts.
RAD50 Antibody - WB detection of Rad50 in HeLa nuclear extracts.

Western blot

RAD50 Antibody - WB detection of Rad50 in HeLa nuclear extracts.
RAD50 Antibody - WB detection of Rad50 in HeLa nuclear extracts.

Western blot

RAD50 Antibody - WB detection of Rad50 in HeLa nuclear extracts.
RAD50 Antibody - WB detection of Rad50 in HeLa nuclear extracts.

Western blot

RAD50 Antibody - WB detection of Rad50 in HeLa nuclear extracts.
RAD50 Antibody - WB detection of Rad50 in HeLa nuclear extracts.

Requested From: United States
Date Requested: 10/19/2018

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