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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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RAC1 Antibody (phospho‑Ser71) LS‑C9853
RAC1 antibody LS-C9853 is an unconjugated rabbit polyclonal antibody to RAC1 from human and mouse. Validated for WB. Cited in 1 publication.
Antibody
Catalog
Size
Price
LS-C9853-100
100 µl
$575

Popular RAC1 Products

Anti-RAC1 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6306 concentration 10 ug/ml.
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin, Western blot, Immunoprecipitation
Antibody
Species: Human
Applications: Flow Cytometry
Antibody
Species: Human
Applications: IHC, Western blot, Immunoprecipitation
Antibody
Species: Human
Applications: Western blot, ELISA

Product Description

RAC1 antibody LS-C9853 is an unconjugated rabbit polyclonal antibody to RAC1 from human and mouse. Validated for WB. Cited in 1 publication.

Specifications

Target
Human RAC1
Synonyms
RAC1, MIG5, p21-Rac1, Ras-like protein TC25, TC25, TC-25, Rac-1
Host
Rabbit
Reactivity
Human, Mouse (tested or 100% immunogen sequence identity)
Predicted
Rat (at least 90% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Protein A purified
Modifications
Unmodified
Applications
  • Western blot (1:1000)
Immunogen
RAC1 antibody was raised against synthetic phosphopeptide (KLH coupled) corresponding to residues surrounding Ser71 of human Rac1 and cdc42.
Epitope
pSer71
Specificity
Detects endogenous Rac1 or cdc42 only when phosphorylated at Ser71. May also recognize phospho-RhoA (Ser73). Species cross-reactivity: Predicted to cross-react with mouse based on sequence homology.
Usage
Western Blot: 1:1000, incubate membrane with diluted antibody in 5% BSA, 1X TBS, 0.1% Tween-20 at 4?C with gentle shaking, overnight.
Presentation
10 mM HEPES, pH 7.5, 150 mM NaCl, 0.1 mg/ml BSA, 50% Glycerol, No preservatives added
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
About RAC1
Plasma membrane-associated small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as secretory processes, phagocytosis of apoptotic cells, epithelial cell polarization and growth-factor induced formation of membrane ruffles. P63000 NM_006908 NP_061485.1


Publications (1)

1
Autocrine IL-8 promotes F-actin polymerization and mediate mesenchymal transition via ELMO1-NF-?B-Snail signaling in glioma. Zhang B, Shi L, Lu S, Sun X, Liu Y, Li H, Wang X, Zhao C, Zhang H, Wang Y. Cancer biology & therapy. 2015 16:898-911. (IHC, WB; Human) [Full Text Article] [PubMed:25870011] [PMC:PMC4623112]

Customer Reviews (0)


Requested From: United States
Date Requested: 10/19/2018

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