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Anti-QPRT Antibody (clone 4E6) LS-C115491

Catalog Size Price
LS-C115491-100 100 µl Unavailable

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16 QPRT Antibodies

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Anti-QPRT Antibody (clone 1C10) LS-C115493
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Anti-QPRT Antibody (clone 7A8) LS-C115527
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100% Guaranteed
Mouse Monoclonal [clone 4E6] (IgG1) to Human QPRT
Human
IHC - Paraffin, Western blot, Flow Cytometry
Unconjugated

Details

Human QPRT
Mouse
IgG1 Monoclonal [4E6]
Unconjugated
Affinity purified
Unmodified

Applications

  • IHC - Paraffin (1:150)
  • Western blot (1:500 - 1:2000)
  • Flow Cytometry (1:100)

Specificity and Use

QPRT antibody was raised against full length human recombinant protein of human QPRT (NP_055113) produced in HEK293T cell
Human QPRT
Concentration: 0.83 mg/ml (Lot dependent)

Packaging

PBS (PH 7.3), 1% BSA, 50% glycerol, 0.02% sodium azide
Store at -20°C. Avoid freeze-thaw cycles.
For research use only.

About QPRT

Q15274 NM_014298 NP_055113.2

QPRT Antibody, QPRTase Antibody, QAPRTase Antibody

QPRT is a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide pathway. Quinolinate acts as a most potent endogenous exitotoxin to neurons. Elevation of quinolinate levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer's disease, and Huntington's disease.

Immunohistochemistry

Immunohistochemistry
Immunohistochemical staining of paraffin-embedded Human liver tissue using anti-QPRT mouse monoclonal antibody.

Immunohistochemistry

Immunohistochemistry
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-QPRT mouse monoclonal antibody.

Immunohistochemistry

Immunohistochemistry
Immunohistochemical staining of paraffin-embedded Human Kidney tissue using anti-QPRT mouse monoclonal antibody.

Western blot

Western blot
Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-QPRT monoclonal antibody.

Western blot

Western blot
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY QPRT (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-QPRT.

Flow Cytometry

Flow Cytometry
HEK293T cells transfected with either overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-QPRT antibody, and then analyzed by flow cytometry.

Requested From: 
Date Requested: 8/18/2017

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