LSBio
Products
  • Antibodies
  • All Antibodies
  • Primary Antibodies
  • Secondary Antibodies
  • IHC-plus Antibodies
  • Isotype Control Antibodies
  • ELISA Kits
  • All Kits
  • Traditional ELISA Kits
  • Cell-Based ELISA Kits
  • DNA-Binding ELISA Kits
  • Phospho-Specific ELISA Kits
  • ELISA Development Kits
  • Chemiluminescent CLIA Kits
  • Proteins
  • All Proteins
  • Recombinant Proteins
  • Native Proteins
  • Over-expression Lysates
  • Cell and Tissue Lysates
  • Bio-active Proteins
  • Animal-free Proteins
  • Synthetic Peptides
  • Biochemicals
  • All Biochemicals

  • Immunohistochemistry
  • Immunohistochemistry Reagents
  • Comprehensive IHC Reports
  • Custom IHC Services
  • TCR Screening Services
  • IHC-plus Antibodies
Services
  • Immunohistochemistry Services

  • Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

  • TCR Screening Services

  • Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Have a question? CustomerSupport@LSBio.com
Research Areas
  • Cancer Research Resources and Products:
  • Breast Cancer
  • Colorectal Cancer
Resources
  • Purchasing
  • Product Ordering Terms and Conditions
  • Holiday Schedule
  • About the LSBio Guarantee
  • About Reviews
  • Reference Material
  • About LSBio (LifeSpan BioSciences Inc.)
  • About Our 2-million Specimen Tissue Bank
  • About Our IHC Validation Process
  • About Our IHC-plus™ Immunohistochemistry Protocol
  • Protocols
  • Secure Logins
  • Login to Our Secure ShareFile Site
  • Login to Our IHC Database
Distributors
Contact Us

LSBio
2401 Fourth Avenue Suite 900
Seattle WA 98121

Phone: 866-819-4732 (Toll Free North America)
206-374-1102 (International)

Fax: 866-206-6909 (Toll Free North America)
206-577-4565 (International)
How to Buy - Details about how to buy our products.

Orders@LSBio.com - To submit a new order.

Customer.Support@LSBio.com - To submit questions about existing orders, pricing, availability, bulk quotes, proforma invoice requests, or other billing issues.

Technical.Support@LSBio.com - To request technical information requests about an LSBio product or its application.

Sales@LSBio.com - To request information about fee-for-service contract IHC studies, IHC reports, distribution agreements, or general business development.

Worldwide Distributors List - To find your local distributor if you're not within the United States.
Login ▾
Wish List
View Cart

Anti-Pyrin / MEFV / MEF Antibody (N-Terminus) LS-C110228

Catalog Size Price
LS-C110228-50 50 µg Unavailable

Most Popular Pyrin / MEFV / MEF Antibodies

Anti-Pyrin / MEFV / MEF Antibody (N-Terminus) LS-C31416
Rabbit Polyclonal (IgG) to Human Pyrin / MEFV / MEF
Human, Monkey, Mouse, Bat, Bovine, Dog, Guinea pig
Western blot
Unconjugated
A: Marker, B: HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Anti-Pyrin / MEFV / MEF Antibody (aa268-284) IHC-plus™ LS-B865
Rabbit Polyclonal to Human Pyrin / MEFV / MEF
Human
IHC, IHC - Paraffin, ELISA
Unconjugated
Anti-MEFV antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B865 concentration 10 ug/ml.
Anti-Pyrin / MEFV / MEF Antibody (aa428-440) LS-C55102
Goat Polyclonal to Human Pyrin / MEFV / MEF
Human
Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Unconjugated
Anti-Pyrin / MEFV / MEF Antibody (clone 4E6) LS-C197669
Mouse Monoclonal [clone 4E6] (IgG2a,k) to Human Pyrin / MEFV / MEF
Human
Western blot, ELISA
Unconjugated
Detection limit for recombinant GST tagged MEFV is approximately 0.1 ng/ml as a capture antibody.
Anti-Pyrin / MEFV / MEF Antibody (aa418-445, Biotin) LS-C262967
Rabbit Polyclonal (IgG) to Human Pyrin / MEFV / MEF
Human
Western blot, ELISA
Biotin Conjugated

100% Guaranteed
Rabbit Polyclonal to Human Pyrin / MEFV / MEF
Human, Horse
Western blot (applications tested for the base form of this product only)
Unconjugated

Details

Human Pyrin / MEFV / MEF
Rabbit
Human, Horse (tested or 100% immunogen sequence identity)
Monkey (at least 90% immunogen sequence identity)
Polyclonal
Unconjugated. Also available conjugated with Biotin, FITC, HRP.
Immunoaffinity purified
Unmodified

Applications

  • Western blot (0.2 - 1 µg/ml)
  • (applications tested for the base form of this product only)

  • IHC - Paraffin

Specificity and Use

Synthetic peptide from N-Terminus of human MEFV (O15553, NP_000234). Percent identity by BLAST analysis: Human, Chimpanzee (100%); Gorilla, Gibbon, Monkey (92%); Horse (84%).
LS-E13616 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C110228. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
N-Terminus
Human MEFV
Western Blot: Suggested dilution at 1 ug/ml in 5% skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody.

Packaging

Lyophilized from PBS with 2% sucrose
Distilled water
Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year); Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.
For research use only.

About Pyrin / MEFV / MEF

O15553 NM_000243 NP_000234.1

MEFV Antibody, Mediterranean fever Antibody, MEF Antibody, Pyrin Antibody, TRIM20 Antibody, FMF Antibody, Marenostrin Antibody

Involved in innate immunity and the inflammatory response. Interacts with several components of the inflammasome complex, a large oligomeric structure which recruits and activates CASP1 and ultimately induces maturation of cytokines such as IL1B. However, the exact role of MEFV in the inflammatory pathway is uncertain as contradictory effects on IL1B processing have been reported in different experimental systems. Has been shown to activate IL1B production (PubMed:16037825).

Western blot

MEFV antibody LS-C110228 Western blot of HepG2 cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
MEFV antibody LS-C110228 Western blot of HepG2 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Requested From: 
Date Requested: 5/25/2018

Get Social With Us! Follow us on Facebook Follow us on Google+ Follow us on LinkedIn PSL Alliance Member
Copyright © 2018 LifeSpan BioSciences, Inc. All Rights Reserved Privacy Policy



Catalog Number