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Anti-Pyrin / MEFV / MEF Antibody (clone 4E6) LS-C197669

Ordering

Wt. Vol. Conc. Price
100 µg - 0.5 mg/ml $355
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
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Most Popular Pyrin / MEFV / MEF Antibodies

Anti-Pyrin / MEFV / MEF Antibody (N-Terminus) LS-C31416
Rabbit Polyclonal (IgG) to Human Pyrin / MEFV / MEF
Human, Monkey, Mouse, Bat, Bovine, Dog, Guinea pig
Western blot
Unconjugated
Western blot Image
Anti-Pyrin / MEFV / MEF Antibody (aa268-284) IHC-plus™ LS-B865
Rabbit Polyclonal to Human Pyrin / MEFV / MEF
Human
IHC - Paraffin, ELISA
Unconjugated
Immunohistochemistry Image
Anti-Pyrin / MEFV / MEF Antibody (clone 4E6) LS-C197669
Mouse Monoclonal [clone 4E6] (IgG2a,k) to Human Pyrin / MEFV / MEF
Human
Western blot, ELISA
Unconjugated
Enzyme-Linked Immunosorbent Assay Image

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Mouse Monoclonal [clone 4E6] (IgG2a,k) to Human Pyrin / MEFV / MEF
Human
Western blot, ELISA
Unconjugated

Details

Human Pyrin / MEFV / MEF
Mouse
Human (tested or 100% immunogen sequence identity)
IgG2a,k Monoclonal [4E6]
Unconjugated
Protein A purified
Unmodified

Applications

  • Western blot
  • ELISA

Specificity and Use

Pyrin / MEFV / MEF antibody was raised against mEFV (NP_000234, aa1-110 partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Human Pyrin / MEFV / MEF
Sandwich ELISA: Recombinant protein. Western Blot: Recombinant protein.

Packaging

PBS, pH 7.4.
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
For research use only.

About Pyrin / MEFV / MEF

O15553 NM_000243 NP_000234.1

MEFV Antibody, Mediterranean fever Antibody, MEF Antibody, Pyrin Antibody, TRIM20 Antibody, FMF Antibody, Marenostrin Antibody

Involved in innate immunity and the inflammatory response. Interacts with several components of the inflammasome complex, a large oligomeric structure which recruits and activates CASP1 and ultimately induces maturation of cytokines such as IL1B. However, the exact role of MEFV in the inflammatory pathway is uncertain as contradictory effects on IL1B processing have been reported in different experimental systems. Has been shown to activate IL1B production (PubMed:16037825).

Enzyme-Linked Immunosorbent Assay

Enzyme-Linked Immunosorbent Assay
Detection limit for recombinant GST tagged MEFV is approximately 0.1 ng/ml as a capture antibody.
 

Requested From: United States
Date Requested: 12/3/2016

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