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Anti-Pyrin / MEFV / MEF Antibody (aa418-445) LS-C157883


Wt. Vol. Conc. Price
- 400 µl - Unavailable

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100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Human Pyrin / MEFV / MEF
Western blot


Human Pyrin / MEFV / MEF
Human (tested or 100% immunogen sequence identity)
Protein A purified


Western blot (1:1000)

Specificity and Use

LS-E6779 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C157883. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
This MEFV antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 418-445 amino acids from the Central region of human MEFV.


PBS, 0.09% sodium azide
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
For research use only.

About Pyrin / MEFV / MEF

O15553 NM_000243 NP_000234.1

MEFV Antibody, Mediterranean fever Antibody, MEF Antibody, Pyrin Antibody, TRIM20 Antibody, FMF Antibody, Marenostrin Antibody

Involved in innate immunity and the inflammatory response. Interacts with several components of the inflammasome complex, a large oligomeric structure which recruits and activates CASP1 and ultimately induces maturation of cytokines such as IL1B. However, the exact role of MEFV in the inflammatory pathway is uncertain as contradictory effects on IL1B processing have been reported in different experimental systems. Has been shown to activate IL1B production (PubMed:16037825).

Western blot

Western blot
MEFV Antibody western blot of ZR-75-1 cell line lysates (35 ug/lane). The MEFV antibody detected the MEFV protein (arrow).

Requested From: 
Date Requested: 4/23/2017

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