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Anti-PYCARD / ASC / TMS1 Antibody (aa182-195) IHC-plus™ LS-B1393

Note: This antibody replaces LS-C381, LS-C92161


Wt. Vol. Conc. Price
50 µg - 1 mg/ml $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

Most Popular PYCARD / ASC / TMS1 Antibodies

Anti-PYCARD / ASC / TMS1 Antibody (clone 3E9) LS-C175123
Mouse Monoclonal [clone 3E9] (IgG1) to Human PYCARD / ASC / TMS1
IHC - Paraffin, Western blot, Flow Cytometry
Immunohistochemistry Image
Anti-PYCARD / ASC / TMS1 Antibody (DY488) LS-C180936
Rabbit Polyclonal to Human PYCARD / ASC / TMS1
Human, Mouse
IHC - Paraffin, ICC, Immunofluorescence
DY488 Conjugated
Immunohistochemistry Image
Anti-PYCARD / ASC / TMS1 Antibody (DY650) LS-C180940
Rabbit Polyclonal to Human PYCARD / ASC / TMS1
Human, Mouse
IHC - Paraffin, ICC
DY650 Conjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Human PYCARD / ASC / TMS1
IHC - Paraffin, ICC, Western blot


Human (tested or 100% immunogen sequence identity)
Immunoaffinity purified


  • IHC - Paraffin (5 µg/ml)
  • ICC
  • Western blot (1 µg/ml)

Specificity and Use

PYCARD / ASC / TMS1 antibody was raised against synthetic peptide from human PYCARD.
LS-E29937 - Liquid - 50 µg - $145.00
synthetic peptide (resqsylvedlers) corresponding to amino acids 182 to 195 of human ASC
Immunohistochemistry: LS-B1393 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B1393 was determined to be 5 ug/ml.


PBS, 0.02% sodium azide.
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
For research use only.


Q9ULZ3 NM_013258 NP_037390.2

PYCARD Antibody, CARD5 Antibody, HASC Antibody, ASC Antibody, TMS Antibody, TMS-1 Antibody, PYD and CARD domain containing Antibody, TMS1 Antibody

Functions as key mediator in apoptosis and inflammation. Promotes caspase-mediated apoptosis involving predominantly caspase-8 and also caspase-9 in a probable cell type-specific manner. Involved in activation of the mitochondrial apoptotic pathway, promotes caspase-8-dependent proteolytic maturation of BID independently of FADD in certain cell types and also mediates mitochondrial translocation of BAX and activates BAX-dependent apoptosis coupled to activation of caspase-9, -2 and -3.


Anti-PYCARD antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1393 concentration 5 ug/ml.


Anti-PYCARD antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1393 concentration 5 ug/ml.


Immunocytochemistry of ASC in HL60 cells with ASC antibody at 5 ug/ml.

Western blot

Western blot
Western blot of ASC in HL60 whole cell lysate in the absence (A) or presence (B) of blocking peptide with ASC antibody at 1 ug /ml.

Requested From: United States
Date Requested: 10/21/2016

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