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PVRL3 / Nectin-3
poliovirus receptor-related 3
Plays a role in cell-cell adhesion through heterophilic trans-interactions with nectin-like proteins or nectins, such as trans-interaction with PVRL2/nectin-2 at Sertoli-spermatid junctions. Trans-interaction with PVR induces activation of CDC42 and RAC small G proteins through common signaling molecules such as SRC and RAP1. Also involved in the formation of cell-cell junctions, including adherens junctions and synapses. Induces endocytosis-mediated down-regulation of PVR from the cell surface, resulting in reduction of cell movement and proliferation. Plays a role in the morphology of the ciliary body.
| Gene Name: | poliovirus receptor-related 3 |
| Synonyms: | PVRL3, CDW113, DKFZP566B0846, Nectin 3, PPR3, Poliovirus receptor-related 3, CD113, CD113 antigen, NECTIN-3, PVRR3 |
| Target Sequences: | NM_015480 NP_056295.1 Q9NQS3 |
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PVRL3 / Nectin-3
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(7)
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(26)
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(8)
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(8)
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(7)
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(4)
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(4)
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(2)
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(1)
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(1)
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(1)
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(1)
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(1)
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(3)
PVRL3 / Nectin-3 Rat anti-Mouse Monoclonal (Extracellular Domain) (103-A1) Antibody
Mouse
ELISA, Flo, IHC, IHC-Fr, IP
Unconjugated
100 µg/$1,001
PVRL3 / Nectin-3 Rat anti-Mouse Monoclonal (aa50-400) (FITC) (103-A1) Antibody
Mouse
Flo, Func, IF, IHC, IHC-Fr, IP
FITC Conjugated
100 µg/$807
PVRL3 / Nectin-3 Rat anti-Mouse Monoclonal (Concentrated) (103-A1) Antibody
Mouse
Flo, IHC, IHC-Fr, IP, WB
Unconjugated, Concentrated
1 ml/$786
PVRL3 / Nectin-3 Mouse anti-Human Monoclonal (6D5B2) Antibody
Human
ELISA, Flo, WB
Unconjugated
100 µg/$459
PVRL3 / Nectin-3 Rabbit anti-Human Polyclonal (aa467-516) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
PVRL3 / Nectin-3 Rat anti-Mouse Monoclonal (Extracellular Domain) (103-A1) Antibody
Mouse
Flo, Func, IF, IHC, IHC-Fr, IP
Unconjugated
100 µg/$652
PVRL3 / Nectin-3 Rabbit anti-Human Polyclonal (aa143-192) Antibody
Human
WB
Unconjugated
100 µl/$424
PVRL3 / Nectin-3 Rat anti-Mouse Monoclonal (aa50-400) (FITC) (13A62) Antibody
Mouse
ELISA, Flo, Func, ICC, IHC, IHC-Fr, IP
FITC Conjugated
100 µg/$910
PVRL3 / Nectin-3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IP, WB
Unconjugated
100 µg/$331
E. coli
His-T7
26.1 kDa
10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176
PVRL3 / Nectin-3 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
PVRL3 / Nectin-3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
PVRL3 / Nectin-3 Mouse anti-Human Monoclonal Antibody
Human
IHC, IHC-P
Unconjugated
100 µl/$412
PVRL3 / Nectin-3 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
PVRL3 / Nectin-3 Mouse anti-Human Monoclonal (1D1) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
PVRL3 / Nectin-3 Rabbit anti-Human Polyclonal (aa507-536) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
PVRL3 / Nectin-3 Rabbit anti-Human Polyclonal (aa507-536) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
PVRL3 / Nectin-3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µl/$412
PVRL3 / Nectin-3 Rabbit anti-Human Polyclonal (160-240 aa, Internal) Antibody
Mouse, Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
PVRL3 / Nectin-3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
PVRL3 / Nectin-3 Rabbit anti-Human Polyclonal (311-360 aa, Internal) Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
PVRL3 / Nectin-3 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
100 µg/$357
PVRL3 / Nectin-3 Rabbit anti-Mouse Polyclonal (aa90-293) Antibody
Mouse, Rat
WB
Unconjugated
100 µl/$306; 200 µl/$347; 500 µl/$484; 1 ml/$553; 2 ml/$737; 5 ml/$1,206
PVRL3 / Nectin-3 Rabbit anti-Human Polyclonal (aa184-233) Antibody
Mouse, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
PVRL3 / Nectin-3 Rabbit anti-Human Polyclonal (aa166-215) Antibody
Mouse, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
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product results
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