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Anti-PV1 / PLVAP Antibody (clone MECA-32, Biotin) LS-C58130

Note: This antibody replaces LS-C58131

Ordering

Wt. Vol. Conc. Price
100 µg - - $235
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular PV1 / PLVAP Antibodies

Anti-PV1 / PLVAP Antibody LS-C124383
Mouse Monoclonal (IgG1) to Human PV1 / PLVAP
Human
IHC, Immunofluorescence, Western blot, Flow Cytometry
Unconjugated
Anti-PV1 / PLVAP Antibody (clone MECA-32) LS-C124385
Rat Monoclonal [clone MECA-32] (IgG2a) to Mouse PV1 / PLVAP
Mouse
IHC - Frozen, Flow Cytometry
Unconjugated
Anti-PV1 / PLVAP Antibody (clone MECA-32) LS-C189749
Rat Monoclonal [clone MECA-32] (IgG2a,k) to Mouse PV1 / PLVAP
Mouse
IHC, ICC, Western blot, Immunoprecipitation, Flow Cytometry
Unconjugated

100% Guaranteed 100% Guaranteed
Rat Monoclonal [clone MECA-32] (IgG2a) to Mouse PV1 / PLVAP
Mouse
IHC - Frozen, Flow Cytometry (applications tested for the base form of this product only)
Biotin Conjugated

Details

Mouse PV1 / PLVAP
Rat
Mouse (tested or 100% immunogen sequence identity)
IgG2a Monoclonal [MECA-32]
Biotin. Also available Unconjugated or conjugated with FITC.
Affinity purified
Unmodified

Applications

  • IHC - Frozen (1:1 - 1:10)
  • Flow Cytometry
  • (applications tested for the base form of this product only)

Specificity and Use

Recognizes murine plasmalemma vesicle-associated protein (PLVAP), a 60kD protein which is otherwise known as MECA-32 and PV-1. PLVAP is a transmembrane homodimer which is associated with endothelial cell caveolae and fenestrae. In adult and embryonic mice, PLVAP is primarily expressed on endothelial tissues but shows restricted distribution in the skeletal, cardiac and brain tissues. In embryonic mice, PLVAP expression, on the vasculature associated with blood brain barrier has been reported to be developmentally regulated. In humans, PLVAP is selectively up-regulated in a variety of high-grade brain tumors, including glioblastoma and metastatic carcinoma, as well as other cerebral disorders associated with blood-brain barrier disruption, such as acute ischemia. PLVAP represents a novel marker of brain tumor angiogenesis and integrity of the blood-brain barrier and is a potential therapeutic target.
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 ul of the suggested working dilution to label 1x10^6 cells in 100 ul. Method sheets are available on request.

Packaging

PBS, pH 7.4, 0.09% sodium azide, 1% BSA.
Long term: -20°C; Short term: -20°C
For research use only.

About PV1 / PLVAP

Q9BX97 NM_031310 NP_112600.1

PLVAP Antibody, gp68 Antibody, FELS Antibody, Plasmalemma vesicle protein 1 Antibody, PV-1 Antibody, PV1 Antibody

Involved in the formation of stomatal and fenestral diaphragms of caveolae. May function in microvascular permeability.

Requested From: United States
Date Requested: 12/2/2016

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