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B001/B101
Shirley, MA 01464
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20700 44th Avenue W
Lynnwood, WA 98036
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PTPRR
protein tyrosine phosphatase, receptor type, R
PTPRR is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domain, and thus represents a receptor-type PTP. Silencing of this gene has been associated with colorectal cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares a symbol (PTPRQ) with another gene, protein tyrosine phosphatase, receptor type, Q (GeneID 374462), which is also located on chromosome 12.
| Gene Name: | protein tyrosine phosphatase, receptor type, R |
| Family/Subfamily: | Protein Phosphatase , R7 receptor |
| Synonyms: | PTPRR, Ch-1 PTPase, Ch-1PTPase, EC-PTP, ECPTP, PTP-SL, NC-PTPCOM1, PC12-PTP1, PCPTP1, R-PTP-R |
| Target Sequences: | NM_002849 NP_002840.2 Q15256 |
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