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PTPRN2 / Phogrin

protein tyrosine phosphatase, receptor type, N polypeptide 2

PTPRN2 / Phogrin is a protein with sequence similarity to receptor-like protein tyrosine phosphatases. However, tyrosine phosphatase activity has not been experimentally validated for this protein. Studies of the rat ortholog suggest that the encoded protein may instead function as a phosphatidylinositol phosphatase with the ability to dephosphorylate phosphatidylinositol 3-phosphate and phosphatidylinositol 4,5-diphosphate, and this function may be involved in the regulation of insulin secretion. This protein has been identified as an autoantigen in insulin-dependent diabetes mellitus. Alternative splicing results in multiple transcript variants.

Gene Name: protein tyrosine phosphatase, receptor type, N polypeptide 2
Family/Subfamily: Protein Phosphatase , R8
Synonyms: PTPRN2, ICAAR, Ia-2 beta, IA-2beta, PTPRP, R-PTP-N2, Phogrin, Ptp-np, IAR, KIAA0387, PTP NE-6, Tyrosine phosphatase IA-2 beta
Target Sequences: NM_002847 NP_002838.2 Q92932

☰ Filters
Antibodies (37)
Proteins (8)
Over-Expression Lysate (2)
Primary (37)
Recombinant (6)
PTPRN2 / Phogrin (45)
Human (29)
Mouse (15)
Rat (7)
IHC (1)
IHC-P (1)
WB (37)
ELISA (14)
IF (1)
Peptide-ELISA (2)
rabbit (37)
Product Group
IHCPlus (1)
IgG (18)
polyclonal pc (37)
APC (2)
APC Conjugated (4)
Azide-free (2)
Biotin Conjugated (4)
Cy3 Conjugated (2)
Cy7 Conjugated (2)
FITC Conjugated (4)
HRP Conjugated (4)
PE Conjugated (4)
Unconjugated (13)
aa161-189 (7)
aa94-125 (7)
180-260 aa, Internal (1)
Internal (1)
aa206-255 (1)
No (45)
GST, N-terminus (1)
His (2)
Myc-DDK (Flag) (3)
Human (5)
Mouse (2)
293T Cells (1)
E. coli (2)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Yeast (2)
Purified (1)
PTPRN2 / Phogrin Antibody - Anti-PTPRN2 / Phogrin antibody IHC staining of human pancreas, islet. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
PTPRN2 / Phogrin Rabbit anti-Human Polyclonal (aa206-255) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$460
PTPRN2 / Phogrin Antibody - PTPRN2 Antibody western blot of A2058 cell line lysates (35 ug/lane). The PTPRN2 antibody detected the PTPRN2 protein (arrow).
Select
PTPRN2 / Phogrin Rabbit anti-Human Polyclonal (aa161-189) Antibody
Human
WB
Unconjugated
400 µl/$393
PTPRN2 / Phogrin Antibody - Staining NIH-3T3 cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
Select
PTPRN2 / Phogrin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
PTPRN2 / Phogrin Antibody - Western blot analysis of Phogrin expression in HeLa (A); SP2/0 (B); H9C2 (C) whole cell lysates.
Select
PTPRN2 / Phogrin Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Human
WB
Unconjugated
100 µl/$299
PTPRN2 / Phogrin Protein
Select
Yeast
His
66.15 kD
1 mg/$1,607; 100 µg/$469; 20 µg/$349
Select
PTPRN2 / Phogrin Rabbit anti-Human Polyclonal (aa94-125) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
Select
PTPRN2 / Phogrin Rabbit anti-Human Polyclonal (aa94-125) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
PTPRN2 / Phogrin Rabbit anti-Human Polyclonal (aa94-125) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
Select
PTPRN2 / Phogrin Rabbit anti-Human Polyclonal (aa94-125) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
Select
PTPRN2 / Phogrin Rabbit anti-Human Polyclonal (aa94-125) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
Select
PTPRN2 / Phogrin Rabbit anti-Human Polyclonal (aa94-125) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
Select
PTPRN2 / Phogrin Rabbit anti-Human Polyclonal (180-260 aa, Internal) Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
Select
PTPRN2 / Phogrin Rabbit anti-Human Polyclonal (aa161-189) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
Select
PTPRN2 / Phogrin Rabbit anti-Human Polyclonal (aa161-189) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
PTPRN2 / Phogrin Rabbit anti-Human Polyclonal (aa161-189) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
Select
PTPRN2 / Phogrin Rabbit anti-Human Polyclonal (aa161-189) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
Select
PTPRN2 / Phogrin Rabbit anti-Human Polyclonal (aa161-189) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
Select
PTPRN2 / Phogrin Rabbit anti-Human Polyclonal (aa161-189) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
PTPRN2 / Phogrin Antibody - Western blot analysis of extracts from NIH/3T3 cells, using PTPRN2 antibody.
Select
PTPRN2 / Phogrin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
PTPRN2 / Phogrin Antibody - Western Blot; Sample: Recombinant protein.
Select
PTPRN2 / Phogrin Rabbit anti-Mouse Polyclonal Antibody
Mouse
WB
Unconjugated
100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261
PTPRN2 / Phogrin Antibody - Western Blot; Sample: Recombinant protein.
Select
PTPRN2 / Phogrin Rabbit anti-Mouse Polyclonal (Biotin) Antibody
Mouse
WB
Biotin Conjugated
100 µl/$321; 200 µl/$369; 500 µl/$527; 1 ml/$611; 2 ml/$842; 5 ml/$1,387
Select
PTPRN2 / Phogrin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
PTPRN2 / Phogrin Antibody - The anti-PTPIA2 beta N-term antibody is used in Western blot to detect PTPIA2 beta in C6 cell lysate.
Select
PTPRN2 / Phogrin Rabbit anti-Human Polyclonal (aa94-125) Antibody
Human
WB
Unconjugated
400 µl/$393
PTPRN2 / Phogrin Antibody - Western Blot; Sample: Recombinant protein.
Select
PTPRN2 / Phogrin Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
PTPRN2 / Phogrin Antibody - Western blot analysis of extracts of various cell lines, using PTPRN2 antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 5s.
Select
PTPRN2 / Phogrin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
Viewing 1-25 of 45 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).