Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human (tested or 100% immunogen sequence identity)
Monkey, Bovine (at least 90% immunogen sequence identity)
Protein G purified
IHC - Paraffin
Specificity and Use
PTPRA / RPTP-Alpha antibody was raised against synthetic peptide from human PTPRA. Percent identity by BLAST analysis: Human, Gorilla, Gibbon (100%); Monkey, Marmoset, Bovine (94%); Rat, Panda, Dog, Rabbit, Horse (88%); Hamster, Bat (82%).
KLH conjugated synthetic peptide comprising amino acids 104 - 120 [NGTWLPDNQFTDARTEP] of the human protein tyrosine phosphatase receptor type A (PTPRA) protein.
PBS, 0.09% sodium azide.
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP.